Evidence map›Paper›PMID 37580508›Full record

ArticleCommunications biology2023

Task-residual effective connectivity of motor network in transient ischemic attack.

Truc Chu, Seonjin Lee, Il-Young Jung, Youngkyu Song, Hyun-Ah Kim, Jong Wook Shin, Sungho Tak

Open access · goldAbstract read
In one paragraph

Article in Communications biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Truc Chu *Research Center for Bioconvergence Analysis, Korea Basic Science Institute, Cheongju, 28119, Republic of Korea.
Seonjin Lee *Research Center for Bioconvergence Analysis, Korea Basic Science Institute, Cheongju, 28119, Republic of Korea.
Il-Young Jung *Department of Rehabilitation Medicine, Chungnam National University Sejong Hospital, Sejong, 30099, Republic of Korea.
Youngkyu SongBio-Chemical Analysis Team, Korea Basic Science Institute, Cheongju, 28119, Republic of Korea.
Hyun-Ah KimDepartment of Rehabilitation Medicine, Chungnam National University Hospital, Daejeon, 35015, Republic of Korea.
Jong Wook ShinDepartment of Neurology, Chungnam National University Sejong Hospital, Sejong, 30099, Republic of Korea. dr.shin@hanmail.net.ORCID http://orcid.org/0000-0002-3988-1680
Sungho TakResearch Center for Bioconvergence Analysis, Korea Basic Science Institute, Cheongju, 28119, Republic of Korea. stak@kbsi.re.kr.ORCID http://orcid.org/0000-0002-3836-0082
Chungnam National University · KRBiocon (Switzerland) · CHChungnam National University Hospital · KRKorea Basic Science Institute · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transient ischemic attack (TIA) is a temporary episode of neurological dysfunction that results from focal brain ischemia. Although TIA symptoms are quickly resolved, patients with TIA have a high risk of stroke and persistent impairments in multiple domains of cognitive and motor functions. In this study, using spectral dynamic causal modeling, we investigate the changes in task-residual effective connectivity of patients with TIA during fist-closing movements. 28 healthy participants and 15 age-matched patients with TIA undergo functional magnetic resonance imaging at 7T. Here we show that during visually cued motor movement, patients with TIA have significantly higher effective connectivity toward the ipsilateral primary motor cortex and lower connectivity to the supplementary motor area than healthy controls. Our results imply that TIA patients have aberrant connections among motor regions, and these changes may reflect the decreased efficiency of primary motor function and disrupted control of voluntary movement in patients with TIA.

Indexed as

Ischemic Attack, TransientAgedFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedMotor Neurons

Identifiers

PMID37580508
PMCPMC10425379
OpenAlexW4385811209

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.