Evidence map›Paper›PMID 37580423›Full record

ArticleCardiovascular and interventional radiology2023

Cryoablation for Bone and Soft Tissue Lesions in Pediatric Patients: Complications and Preventive Measures.

Kumar Kempegowda Shashi, Mohamed M Shahin, Patrick Johnston, Raja Shaikh

Abstract read
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In one paragraph

Article in Cardiovascular and interventional radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
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  6. Tumor ablation in children.Pediatric radiology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Kumar Kempegowda ShashiDepartment of Radiology, Arkansas Children's Hospital, 1 Children's Way, Little Rock, AR, 72202, USA.
Mohamed M ShahinDepartment of Radiology, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA, 02115, USA.
Patrick JohnstonDepartment of Radiology, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA, 02115, USA.
Raja ShaikhDepartment of Radiology, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA, 02115, USA. raja.shaikh@childrens.harvard.edu.ORCID http://orcid.org/0000-0002-2176-6334
Boston Children's Hospital · USArkansas Children's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate complications associated with cryoablation in a pediatric population and review preventive measures to mitigate these complications. MATERIAL AND

methodsRetrospective study including all the image guided cryoablations performed on pediatric population. Immediate and delayed complications were analyzed, and we identified the different protective measures used and the clinical outcomes from follow-up. Point estimates for the percentage of complications were calculated by maximum likelihood, and 95% confidence intervals for the true percentages were calculated using the Clopper-Pearson exact method.

resultsEighty-seven ablations were performed on 68 patients (age range of 2-18 years, mean 12.4 years) for non-neoplastic (70%) and neoplastic (30%) lesions. The percentage of ablations resulting in complications was 18% (95% confidence interval (CI) 11% to 28%). Of these, 5% (95% CI 1% to 11%) were grade 3 complications, and 14% (95% CI 7% to 23%) were grade 2 complications. Thermal protection was performed in 27.6% of ablations (n = 24). The mean clinical follow-up duration was 348 days.

conclusionCryoablation in pediatric patients is relatively safe, with a major complication rate per ablation of 5%. Thermal protective measures can be considered to mitigate these complications.

Indexed as

CryosurgeryAdolescentChildChild, PreschoolHumansRetrospective StudiesTreatment OutcomeComplicationsCryoablationPediatricPediatric tumorsSoft tissue tumorsVascular malformations

Identifiers

PMID37580423
OpenAlexW4385800403

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.