ArticleCardiovascular and interventional radiology2023
Six-Month Outcomes of Mechanical Thrombectomy for Treating Deep Vein Thrombosis: Analysis from the 500-Patient CLOUT Registry.
Article in Cardiovascular and interventional radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
ClotTriever Outcomes (CLOUT) Registry
Acute and Subacute Iliofemoral and/or Caval Deep Vein Thrombosis: Evaluation of Mechanical Thrombectomy Systems in a Monocentric, Observational Retrospective and Prospective Study (ASTER Study)
Who cites it
19 citing papers in PubMed, 32 citations in OpenAlex.
- Comparison of anticoagulation vs mechanical thrombectomy for the treatment of iliofemoral deep vein thrombosis.Journal of vascular surgery. Venous and lymphatic disorders · 2024Trial
- Article
- Mechanical thrombectomy and venous-dedicated stent implantation for acute iliofemoral deep vein thrombosis with iliac vein compression.Journal of cardiology cases · 2026Article
- Venous mechanical thrombectomy for deep vein thrombosis in patients with cancer: a single-center prospective study.Blood vessels, thrombosis & hemostasis · 2026Article
- Histologic Diagnosis of Intravascular Large B-Cell Lymphoma After Endovascular Thrombectomy: A Case Report of a Rare and Incidental Finding.Reports (MDPI) · 2026Article
- Midterm clinical outcomes of mechanical versus rheolytic thrombectomy for iliofemoral or iliocaval deep vein thrombosis.Journal of vascular surgery. Venous and lymphatic disorders · 2026Observational
- A case report of May-Thurner syndrome presenting with anticoagulation-refractory iliofemoral deep vein thrombosis successfully treated by aspiration thrombectomy and iliac vein stenting.European heart journal. Case reports · 2026Article
- Contemporary Challenges in Venous Thromboembolism: Evolving Populations and Implications for Management and Risk Stratification.Journal of clinical medicine · 2026Review
- Mechanical Thrombectomy for the Treatment of Iliofemoral Deep Venous Thrombosis using the ClotTriever System: A Single-Centre Experience.Cardiovascular and interventional radiology · 2025Article
- Successful ClotTriever thrombectomy in extensive inferior vena cava and bilateral iliac vein thrombosis with pulmonary embolism.Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery · 2025Article
- Molecular Mechanism of Notch Signaling and Macrophages in Deep Vein Thrombosis: A Comprehensive Review.Cell biochemistry and biophysics · 2025Review
- Iatrogenic arteriovenous fistula after endovenous mechanical thrombectomy.Journal of vascular surgery cases and innovative techniques · 2024Article
- Efficacy and Safety of Direct Oral Anticoagulants After Mechanical Thrombectomy in Venous Thromboembolism: A Comparative Study of 55 Patients.Medical science monitor : international medical journal of experimental and clinical research · 2024Article
- Acute kidney injury requiring dialysis after endovascular intervention for acute deep venous thrombosis: A case report and literature review.Clinical case reports · 2024Article
- Comparative Effectiveness of Thrombectomy Devices in Deep Vein Thrombosis: A Step Forward.Journal of the Society for Cardiovascular Angiography & Interventions · 2024Article
- One-Year Clinical Outcomes Following Mechanical Thrombectomy for Deep Vein Thrombosis: A CLOUT Registry Analysis.Journal of the Society for Cardiovascular Angiography & Interventions · 2024Article
- Mechanical thrombectomy of venous in-stent thrombosis with the novel RevCore thrombectomy system: A report of 2 cases.Radiology case reports · 2024Article
- Critical Care Management of Acute Venous Thromboembolism: Integrating Pharmacotherapy, Thrombectomy, and Temporary Mechanical Support.US cardiology · 2024Review
- Single-center experience with the ClotTriever BOLD catheter for deep vein thrombosis percutaneous mechanical thrombectomy of the lower extremity.Frontiers in surgery · 2023Article
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Authors and funding
26 authors at 20 institutions in 1 country.
Funding
Abstract
purposeMechanical thrombectomy for the treatment of deep vein thrombosis (DVT) is being increasingly utilized to reduce symptoms and prevent postthrombotic syndrome (PTS), but more data on clinical outcomes are needed. Mechanical thrombectomy was studied in the ClotTriever Outcomes (CLOUT) registry with 6-month full analysis outcomes reported herein. MATERIALS AND
methodsThe CLOUT registry is a prospective, all-comer study that enrolled 500 lower extremity DVT patients across 43 US sites treated with mechanical thrombectomy using the ClotTriever System. Core-lab assessed Marder scores and physician-assessed venous patency by duplex ultrasound, PTS assessment using Villalta score, venous symptom severity, pain, and quality of life scores through 6 months were analyzed. Adverse events were identified and independently adjudicated.
resultsAll-cause mortality at 30 days was 0.9%, and 8.6% of subjects experienced a serious adverse event (SAE) within the first 30 days, 1 of which (0.2%) was device related. SAE rethrombosis/residual thrombus incidence was 4.8% at 30 days and 8.0% at 6 months. Between baseline and 6 months, venous flow increased from 27.2% to 92.5% of limbs (P < 0.0001), and venous compressibility improved from 28.0% to 91.8% (P < 0.0001), while median Villalta scores improved from 9.0 at baseline to 1.0 at 6 months (P < 0.0001). Significant improvements in venous symptom severity, pain, and quality of life were also demonstrated. Outcomes from iliofemoral and isolated femoral-popliteal segments showed similar improvements.
conclusionOutcomes from the CLOUT study, a large prospective registry for DVT, indicate that mechanical thrombectomy is safe and demonstrates significant improvement in symptoms and health status through 6 months. Level of Evidence 3: Non-randomized controlled cohort/follow-up study.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.