Clinical Reasoning: A Young Adult With New Seizures and Chapeau de Gendarme.

Alexandria Valdrighi, Anne G Douglas, Robert C Knowlton, Maulik Shah, Jonathan K Kleen

Abstract readCase Reports

In one paragraph

Article in Neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alexandria ValdrighiFrom the Department of Child Neurology (A.V.), University of California, San Francisco; Department of Neurology (A.G.D.), University of Pennsylvania, Philadelphia; and Department of Neurology (R.C.K., M.S., J.K.K.), University of California, San Francisco. alexandria.valdrighi@ucsf.edu.ORCID 0000-0001-5596-3275

Anne G DouglasFrom the Department of Child Neurology (A.V.), University of California, San Francisco; Department of Neurology (A.G.D.), University of Pennsylvania, Philadelphia; and Department of Neurology (R.C.K., M.S., J.K.K.), University of California, San Francisco.ORCID 0009-0008-6877-8974

Robert C KnowltonFrom the Department of Child Neurology (A.V.), University of California, San Francisco; Department of Neurology (A.G.D.), University of Pennsylvania, Philadelphia; and Department of Neurology (R.C.K., M.S., J.K.K.), University of California, San Francisco.

Maulik ShahFrom the Department of Child Neurology (A.V.), University of California, San Francisco; Department of Neurology (A.G.D.), University of Pennsylvania, Philadelphia; and Department of Neurology (R.C.K., M.S., J.K.K.), University of California, San Francisco.ORCID 0009-0007-0261-7054

Jonathan K KleenFrom the Department of Child Neurology (A.V.), University of California, San Francisco; Department of Neurology (A.G.D.), University of Pennsylvania, Philadelphia; and Department of Neurology (R.C.K., M.S., J.K.K.), University of California, San Francisco.ORCID 0000-0003-2622-3205

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The evaluation of new seizures is a common clinical query for neurologists. It can be challenging to delineate between the numerous etiologies of new focal or generalized seizures and, if focal, to localize their onset. In this case report, we present a 26-year-old patient with a new onset of stereotyped events concerning for seizures featuring facial grimacing, dystonic left-hand posturing, and convulsions with immediate return to baseline. Throughout the case, we highlight a stepwise diagnostic approach to the evaluation of new-onset seizures, discuss clues that seizure semiology can provide for localization of ictal onset, and review a novel and atypical presentation of a disease entity frequently encountered by neurologists.

Indexed as

ElectroencephalographySeizuresAdultClinical ReasoningHumansYoung Adult

Identifiers

PMID37580161

DOI10.1212/WNL.0000000000207827

PMCPMC10634645

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.