ArticleNephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association2024
Health-related quality of life and symptom burden in patients on haemodialysis.
Article in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07186361 (Remote Symptom Assessment And Management Via Mobile App For Adults With Chronic Kidney Disease Living In Vietnam), which is not on this map. Cited by 20 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Remote Symptom Assessment And Management Via Mobile App For Adults With Chronic Kidney Disease Living In Vietnam
Who cites it
20 citing papers in PubMed.
- The impact of predialytic oral protein-based supplements on nutritional status and quality of life in hemodialysis patients: a randomized clinical trial.BMC nephrology · 2025Trial
- Quality of Life Among End-Stage Renal Disease Patients Undergoing Maintenance Hemodialysis at King Abdulaziz Hospital, Kingdom of Saudi Arabia: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2026Article
- Article
- Examining Quality-of-Life Priorities of Older Adults Receiving Hemodialysis: A Q-Methodology Study.Kidney medicine · 2026Article
- Article
- Family support, stigma, and psychological detachment in hemodialysis patients: a cross-sectional mediation analysis.BMC nephrology · 2026Article
- Quality of life, sleep quality, and psychological wellbeing of patients with chronic kidney disease in Sabaragamuwa Province, Sri Lanka: a descriptive cross-sectional study.Scientific reports · 2026Article
- Factors associated with employment in end-stage kidney disease patients at the initiation of chronic dialysis or kidney transplantation-a national register-based cohort study.BMC public health · 2026Article
- Dual trajectories of capacity management behavior and quality of life in hemodialysis patients: a longitudinal study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Article
- Correlation between symptom distress and quality of life in patients with Chronic Kidney Disease Stage 5 undergoing hemodialysis in China: a multi-center cross-sectional study.Frontiers in psychiatry · 2026Article
- The Influence of Different Kidney Replacement Modalities on Health-Related Quality of Life in Patients with ESKD.Kidney360 · 2025Article
- Impact of COVID-19 on place of death for disease-related causes: a population-based study in Nanchang, China.Scientific reports · 2025Observational
- Enhancing Nephrology Research with Natural Language Processing and Artificial Intelligence: A Case for More Comprehensive Symptom Documentation.Kidney360 · 2025Article
- Fatigue across different chronic kidney disease populations: experiences and needs of patients.Clinical kidney journal · 2025Article
- Comprehensive Insights into Sarcopenia in Dialysis Patients: Mechanisms, Assessment, and Therapeutic Approaches.Medicina (Kaunas, Lithuania) · 2025Review
- Burden of hemodialysis on health-related quality of life: insights from a multi-center cross-sectional analysis in Southern Albania.Frontiers in medicine · 2025Article
- Early Diagnosis and Timely Terlipressin in Hepatorenal Syndrome Improves Projected Outcomes and Lowers Cost.ClinicoEconomics and outcomes research : CEOR · 2025Article
- Hemoincompatibility in Hemodialysis-Related Therapies and Their Health Economic Perspectives.Journal of clinical medicine · 2024Article
- Association between cognitive functioning and health-related quality of life and its mediation by depressive symptoms in older patients with kidney failure.Journal of nephrology · 2024Observational
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
backgroundPatients on haemodialysis (HD) generally experience poor health-related quality of life (HRQoL) and a broad range of physical and mental symptoms, but it is unknown whether this differs between younger and older patients. We aimed to describe the trajectories of HRQoL and symptom burden of patients <70 and ≥70 years old and to assess the impact of symptom burden on HRQoL.
methodsIn incident Dutch HD patients, HRQoL and symptoms were measured with the 12-item Short Form Health Survey and Dialysis Symptom Index. We used linear mixed models for examining the trajectories of HRQoL and symptom burden during the first year of dialysis and linear regression for the impact of symptom burden on HRQoL.
resultsIn 774 patients, the trajectories of physical HRQoL, mental HRQoL and symptom burden were stable during the first year of dialysis. Compared with patients <70 years of age, patients ≥70 years reported similar physical HRQoL {mean difference -0.61 [95% confidence interval (CI) -1.86-0.63]}, better mental HRQoL [1.77 (95% CI 0.54-3.01)] and lower symptom burden [-2.38 (95% CI -5.08-0.32)]. With increasing symptom burden, physical HRQoL declined more in older than in younger patients (β = -0.287 versus -0.189, respectively; P-value for interaction = .007). For mental HRQoL, this decrease was similar in both age groups (β = -0.295 versus -0.288, P = .847).
conclusionOlder HD patients generally experience a better mental HRQoL and a (non-statistically significant) lower symptom burden compared with younger patients. Their physical HRQoL declines more rapidly with increasing symptom burden.
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