Evidence map›Paper›PMID 37579108›Full record

Trial reportJournal of addiction medicine

An Open-label Pilot Study of NicoBloc as a Novel Smoking Cessation Intervention.

Keith R Chichester, Michelle L Sisson, Sofia Mildrum Chana, Caitlin Wolford-Clevenger, Mickeah J Hugley, Elizabeth S Hawes, Paige Palenski, Angela Nguyen, Jennifer Dahne, Peter S Hendricks and 1 more

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of addiction medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 97% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Keith R ChichesterFrom the Department of Psychiatry and Behavioral Neurobiology, University of Alabama at Birmingham, Birmingham, AL (KRC, MLS, SMC, CW-C, MJH, ESH, PP, AN, KLC); Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC (JD); Hollings Cancer Center, Medical University of South Carolina, Charleston, SC (JD); and School of Public Health, University of Alabama at Birmingham, Birmingham, AL (PSH).
Michelle L Sisson
Sofia Mildrum Chana
Caitlin Wolford-Clevenger
Mickeah J Hugley
Elizabeth S Hawes
Paige Palenski
Angela Nguyen
Jennifer Dahne
Peter S Hendricks
Karen L Cropsey
University of Alabama at Birmingham · US

Funding

In Vivo Experience with NRT to Increase Adherence and Smoking AbstinenceR01DA039678 · NIDA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CROPSEY, KAREN L · 2016 to 2020
$2.6M
Development and Testing of a Depression-Specific Behavioral Activation Mobile App Paired with Nicotine Replacement Therapy Sampling for Smoking Cessation Treatment Via Primary CareK23DA045766 · NIDA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI DAHNE, JENNIFER RENEE · 2018 to 2022
$1.0M
NIDA NIH HHS K23 DA045766NIDA NIH HHS R01 DA039678
6 · The paper itself

Abstract

introductionNicoBloc is a viscous fluid applied to the cigarette filter designed to block tar and nicotine. This novel and understudied smoking cessation device presents a nonpharmacological means for smokers to gradually reduce nicotine and tar content while continuing to smoke their preferred brand of cigarette. This pilot study aimed to assess the feasibility, acceptability, and initial efficacy of NicoBloc as compared with nicotine replacement therapy (nicotine lozenge).

methodsA community sample of predominately Black smokers (N = 45; 66.7% Black) were randomized to receive NicoBloc or nicotine lozenge. Both groups engaged in 4 weeks of smoking cessation therapy followed by 2 months of independent usage with monthly check-ins to assess medication adherence. The intervention lasted 12 weeks, and the study concluded with a 1-month postintervention follow-up visit (week 16).

resultsNicoBloc was comparable with nicotine lozenge in smoking reduction, feasibility, symptom adverse effects, and reported acceptability at week 16. Participants in the lozenge group endorsed higher treatment satisfaction ratings during the intervention and lower cigarette dependence. Adherence to NicoBloc was superior throughout the study.

conclusionNicoBloc was feasible and acceptable to community smokers. NicoBloc presents a unique, nonpharmacological intervention. Future research is needed to examine whether this intervention may be most effective in subpopulations where pharmacological approaches are restricted or in combination with established pharmacological methods such as nicotine replacement therapy.

Indexed as

NicotineSmoking CessationHumansPilot ProjectsTabletsTobacco Use Cessation DevicesNicotineTablets

Identifiers

PMID37579108
PMCPMC10480353
OpenAlexW4323293844

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.