Evidence map›Paper›PMID 37579082›Full record

ArticleACS nano2023

Endoproteolysis of Oligopeptide-Based Coacervates for Enzymatic Modeling.

Zhicheng Jin, Chuxuan Ling, Wonjun Yim, Yu-Ci Chang, Tengyu He, Ke Li, Jiajing Zhou, Yong Cheng, Yi Li, Justin Yeung and 6 more

Open access · greenAbstract read
In one paragraph

Article in ACS nano, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Surface Engineered Biomolecular Condensates for Targeted Cell Cytotoxicity.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  3. Article
  4. Chemistry of materials : a publication of the American Chemical Society · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 2 countries.

Zhicheng JinDepartment of NanoEngineering, University of California, San Diego, La Jolla 92093, California, United States.ORCID 0000-0001-6072-7533
Chuxuan LingDepartment of NanoEngineering, University of California, San Diego, La Jolla 92093, California, United States.
Wonjun YimMaterials Science and Engineering Program, University of California, San Diego, La Jolla 92093, California, United States.ORCID 0000-0002-0242-7898
Yu-Ci ChangMaterials Science and Engineering Program, University of California, San Diego, La Jolla 92093, California, United States.ORCID 0000-0001-6997-9884
Tengyu HeMaterials Science and Engineering Program, University of California, San Diego, La Jolla 92093, California, United States.ORCID 0000-0002-6767-4849
Ke LiInstitute of Materials Research and Engineering (IMRE), Agency for Science, Technology and Research (A*STAR), 2 Fusionopolis Way, Innovis #08-03, Singapore 138634, Republic of Singapore.ORCID 0000-0002-3140-3983
Jiajing ZhouDepartment of NanoEngineering, University of California, San Diego, La Jolla 92093, California, United States.
Yong ChengDepartment of NanoEngineering, University of California, San Diego, La Jolla 92093, California, United States.
Yi LiDepartment of NanoEngineering, University of California, San Diego, La Jolla 92093, California, United States.
Justin YeungDepartment of Bioengineering, University of California, San Diego, La Jolla 92093, California, United States.ORCID 0000-0001-8615-5895
Ruijia WangDepartment of Pediatrics, School of Medicine, University of California, San Diego, La Jolla 92093, California, United States.
Pavla FajtováSkaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla 92093, California, United States.
Lubna AmerMaterials Science and Engineering Program, University of California, San Diego, La Jolla 92093, California, United States.ORCID 0000-0001-5715-5060
Hedi MattoussiDepartment of Chemistry and Biochemistry, Florida State University, Tallahassee 32306, Florida, United States.ORCID 0000-0002-6511-9323
Anthony J O'DonoghueSkaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla 92093, California, United States.
Jesse V JokerstDepartment of NanoEngineering, University of California, San Diego, La Jolla 92093, California, United States.ORCID 0000-0003-2829-6408
University of California San Diego · USAgency for Science, Technology and Research · SGFlorida State University · US

Funding

Validation of Smart Masks for Surveillance of COVID-19R01DE031114 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JOKERST, JESSE VINCENT · 2021 to 2023
$1.2M
VEVO 3100 + LAXR-X Acoustic Imaging SystemS10OD032268 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JOKERST, JESSE VINCENT · 2022 to 2022
$893k
Non-Invasive Detection and Staging of Decubitus and Diabetic UlcersR21AG065776 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JOKERST, JESSE VINCENT · 2020 to 2021
$575k
Imaging SARS-CoV-2 proteases for spatio-temporal insight into Covid-19R21AI157957 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JOKERST, JESSE VINCENT · 2020 to 2020
$434k
NIAID NIH HHS R21 AI157957NIA NIH HHS R21 AG065776NIDCR NIH HHS R01 DE031114NIH HHS S10 OD032268
6 · The paper itself

Abstract

Better insights into the fate of membraneless organelles could strengthen the understanding of the transition from prebiotic components to multicellular organisms. Compartmentalized enzyme reactions in a synthetic coacervate have been investigated, yet there remains a gap in understanding the enzyme interactions with coacervate as a substrate hub. Here, we study how the molecularly crowded nature of the coacervate affects the interactions of the embedded substrate with a protease. We design oligopeptide-based coacervates that comprise an anionic Asp-peptide (D

Indexed as

PeptidesProteinsOligopeptidesPeptide HydrolasesOligopeptidesPeptide HydrolasesPeptidesProteinsdisassemblyenergy transferenzyme kineticsmain proteasePeptide coacervates

Identifiers

PMID37579082
PMCPMC10614163
OpenAlexW4385802818

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.