ArticleEndocrine connections2023
Trend in global burden attributable to low bone mineral density in different WHO regions: 2000 and beyond, results from the Global Burden of Disease (GBD) study 2019.
Article in Endocrine connections, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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19 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Fatty acid dietary intakes and blood concentrations in relation to hip fracture risk in adults: a systematic review and meta-analysis of prospective cohort studies.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025Pooled it
- The efficacy and safety of Gukang Capsule for primary osteoporosis: a systematic review and meta-analysis of randomized clinical trial.Frontiers in pharmacology · 2024Pooled it
- Burden and temporal trends attributable to low bone mineral density in Mexico, 1990-2023: a global burden of disease analysis.Archives of osteoporosis · 2026Article
- Expert consensus on osteoporosis risk management in patients with sleep disorders.Bone research · 2026Review
- Global burden of fall-related injuries attributable to low bone mineral density in women aged 50-69 years: inequalities, projections to 2050, and Mendelian randomisation.Journal of global health · 2026Article
- Adherence to Chinese Dietary Guidelines Is Associated with Better Bone Status in School-Aged Children and Adolescents.Nutrients · 2026Article
- Development and Validation of a Machine Learning Model for Predicting Osteoporosis in Patients with Parkinson's Disease.Neuropsychiatric disease and treatment · 2026Article
- Investigating the Role of Exercise in Improving Bone Health Among Elderly Women with Osteopenia.Journal of functional morphology and kinesiology · 2025Article
- [Attributable disease burden of low bone mineral density related fractures in people over 50 years old from 1990 to 2023 in China].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2025Article
- Clinical manifestations and quality of life of postmenopausal women with severe osteoporosis: a cross-sectional study on the Vietnamese population.BMC women's health · 2025Article
- The prevalence of low bone mineral density in women aged 55 years or older and the association with socioeconomic factors across the Globe.BMC public health · 2025Article
- Exercise interventions to improve bone mineral density in athletes participating in low-impact sports: a scoping review.BMC musculoskeletal disorders · 2025Article
- Burden of falls associated with low bone density globally, in China and ASEAN countries: 1990-2021 trends and projections to 2035.Frontiers in medicine · 2025Article
- Global epidemiology, burden, and causes of lower extremity and pelvic fractures in the past 32 years.Frontiers in public health · 2025Article
- Evolution of Low Bone Mineral Density Impact on Older Adults in the Western Pacific: Socio-Demographic and Health Workforce Perspectives (1990-2021).Risk management and healthcare policy · 2025Article
- Molecular Signaling Pathways and MicroRNAs in Bone Remodeling: A Narrative Review.Diseases (Basel, Switzerland) · 2024Review
- The association between osteoporosis and quality of life among older adults in Southern Iran: findings from the Bushehr Elderly Health Program.BMC geriatrics · 2024Article
- Biocompatibility and Osteogenic Activity of Samarium-Doped Hydroxyapatite-Biomimetic Nanoceramics for Bone Regeneration Applications.Biomimetics (Basel, Switzerland) · 2024Article
- Editorial: Community series - reducing the burden of age-related disease in relation to osteoporosis, sarcopenia and osteosarcopenia, volume II.Frontiers in medicine · 2023Article
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9 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Background: We aimed to document the current state of exposure to low bone mineral density (BMD) and trends in attributable burdens between 2000 and 2019 globally and in different World Health Organization (WHO) regions using the Global Burden of Disease (GBD) study 2019. Methods: We reviewed the sex-region-specific summary exposure value (SEV) of low BMD and the all-ages numbers and age-standardized rates of disability-adjusted life years (DALYs), years lived with disability (YLDs), years of life lost (YLLs), and deaths attributed to low BMD. We compared different WHO regions (Africa, the Eastern Mediterranean Region, Europe, Region of the Americas, Southeast Asia, and Western Pacific), age categories, and sexes according to the estimates of the GBD 2019 report. Results: The global age-standardized SEV of low BMD is estimated to be 20.7% in women and 11.3% in men in 2019. Among the WHO regions, Africa had the highest age-standardized SEV of low BMD in women (28.8% (95% uncertainty interval 22.0-36.3)) and men (16.8% (11.5-23.8)). The lowest SEV was observed in Europe in both women (14.7% (9.9-21.0)) and men (8.0% (4.3-13.4)). An improving trend in the global rate of DALY, death, and YLL was observed during 2000-2019 (-5.7%, -4.7%, and -11.9% change, respectively); however, the absolute numbers increased with the highest increase observed in global YLD (70.9%) and death numbers (67.6%). Southeast Asia Region had the highest age-standardized rates of DALY (303.4 (249.2-357.2)), death (10.6 (8.5-12.3)), YLD (133.5 (96.9-177.3)), and YLL (170.0 (139-197.7)). Conclusions: Overall, the highest-burden attributed to low BMD was observed in the Southeast Asia Region. Knowledge of the SEV of low BMD and the attributed burden can increase the awareness of healthcare decision-makers to adopt appropriate strategies for early screening, and also strategies to prevent falls and fragility fractures and their consequent morbidity and mortality.
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