Evidence map›Paper›PMID 37578619›Full record

ArticleInflammopharmacology2024

Sesquiterpene from Artemisia argyi seed extracts: A new anti-acute peritonitis agent that suppresses the MAPK pathway and promotes autophagy.

Yinchao Li, Yuanhui Wang, Tianxin Li, Zhenzhen Li, Tao Guo, Guimin Xue, Yongtao Duan, Yongfang Yao

Abstract read
PubMed Publisher
In one paragraph

Article in Inflammopharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 10 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Yinchao Li *School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, China.
Yuanhui Wang *School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, China.
Tianxin LiSchool of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, China.
Zhenzhen LiSchool of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, China.
Tao GuoCollege of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450046, China.
Guimin XueCollege of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450046, China. xueguimin123@126.com.
Yongtao DuanHenan Provincial Key Laboratory of Children's Genetics and Metabolic Diseases, Children's Hospital Affiliated to Zhengzhou University, Zhengzhou University, Zhengzhou, 450018, China. duanyongtao860409@163.com.
Yongfang YaoSchool of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, China. yongfangyao@zzu.edu.cn.ORCID http://orcid.org/0000-0001-6455-1213
Zhengzhou University · CNFirst Affiliated Hospital of Henan University · CNMinistry of Education · NZ

Funding

The Joint Fund of Provincial Science and Technology Research and Development plan of Henan Province 222301420057The Open Project of Henan International Joint Laboratory of Prevention and Treatment of PediatricDiseases EKB202202The Open Project of Henan Neurodevelopment Engineering Research Center for Children SG202201
6 · The paper itself

Abstract

To find novel anti-inflammatory drugs, we screened anti-inflammatory compounds from 18 different types of Artemisia argyi seed extracts. The in vitro and in vivo anti-inflammatory activities of the screened compounds and their mechanisms were characterized. We first detected the cytotoxic effect of the compounds on RAW264.7 cells and the inhibitory effect on LPS-induced NO release. It was found that sesquiterpenoids CA-2 and CA-4 had low cytotoxic and strong NO inhibitory activity with an IC

Indexed as

ArtemisiaPeritonitisSesquiterpenesAnimalsAnti-Inflammatory AgentsAutophagyLipopolysaccharidesMicePhosphatidylinositol 3-KinasesPlant ExtractsAnti-Inflammatory AgentsLipopolysaccharidesPhosphatidylinositol 3-KinasesPlant ExtractsSesquiterpenesAcute peritonitisAnti-inflammatory agentsArtemisia argyi seed extractsAutophagyMacrophage

Identifiers

PMID37578619
OpenAlexW4385798461

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.