ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2024
Cutoff values of axial length/corneal radius ratio for determining myopia vary with age among 3-18 years old children and adolescents.
Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Axial Length to Corneal Curvature Ratio is Insufficient for Detecting Pseudomyopia in Children: A Multi-Cohort Study.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026Article
- Myopia Prevalence, Ocular Metrics and Visual Activity in United States Optometry Students.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026Article
- Early identification of myopia risk in children through school-based vision screening: a longitudinal cohort study.BMC public health · 2026Article
- Gender differences in higher-order aberrations and refractive error in Japanese school children: the Kyoto Childhood Refractive Error Study (KRES).Japanese journal of ophthalmology · 2026Observational
- Significant ocular residual astigmatism reduces the effect of orthokeratology lenses in controlling myopia.Scientific reports · 2026Article
- Artificial intelligence-quantified fundus tessellated density and its association with myopia severity in Chinese children: a cross-sectional study.Frontiers in cell and developmental biology · 2026Article
- Correlation between ocular biological parameters and cycloplegic refractive shift in pediatric myopia.International journal of ophthalmology · 2026Article
- Tracking myopia development through axial length progression: a retrospective longitudinal study.Annals of medicine · 2025Article
- Comparison of ocular residual astigmatism between children with clinically significant and non-significant astigmatism.BMC ophthalmology · 2025Article
- Exploration of visual perception metrics as indicators for myopia screening.Lasers in medical science · 2025Article
- Significant Loss of Coordination Among Astigmatism Components in Young Chinese Adults With High Myopia.Translational vision science & technology · 2025Article
- Relationship between the axial length/corneal radius of curvature ratio and hyperopia reserve in preschool children aged 3 - 6 years.BMC ophthalmology · 2025Article
- Ocular Biometry Distribution and One-Year Growth in Eight-Year-Old Southern European Schoolchildren Under the CISViT Project.Children (Basel, Switzerland) · 2025Article
- Ocular biometric parameters in South-Indian children with myopia - A hospital-based retrospective descriptive analysis.Indian journal of ophthalmology · 2025Article
- Cutoff Values of Noncycloplegic Spherical Equivalent Refraction for Myopia Detection in Southwestern Chinese Children.Journal of ophthalmology · 2025Article
- Ocular biological characteristics of children with myopia and rapid axial length changes treated with spectacles with highly aspherical lenslets.International journal of ophthalmology · 2025Article
- Prediction of myopia based on biometric parameters of 500,000 children and adolescents aged 3-18 years.Frontiers in public health · 2025Article
- Refraction and ocular biometric parameters in 3-to 6-year-old preschool children : a large-scale population-based study in Chengdu, China.BMC ophthalmology · 2024Article
- Article
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
purposeTo investigate the effectiveness and cutoffs of axial length/corneal radius (AL/CR) ratio for myopia detection in children by age.
methodsTotally, 21 kindergartens and schools were enrolled. Non-cycloplegic autorefraction (NCAR), axial length (AL), horizontal and vertical meridian of corneal radius (CR1, CR2), and cycloplegic autorefraction were measured. Receiver operating characteristic (ROC) curve was used to obtain the effectiveness and cutoff for myopia detection.
resultsFinally, 7803 participants aged 3-18 years with mean AL/CR ratio of 2.99 ± 0.16 were included. Area under the ROC curve (AUC) of AL/CR ratio for myopia detection (0.958 for AL/CR1, 0.956 for AL/CR2, 0.961 for AL/CR) was significantly larger than that of AL (0.919, all P < 0.001), while AUCs of the three were similar with different cutoffs (> 2.98, > 3.05, and > 3.02). When divided by age, the ROC curves of AL/CR ratio in 3- to 5-year-olds showed no significance or low accuracy (AUCs ≤ 0.823) in both genders. In ≥ 6-year-olds, the accuracies were promising (AUCs ≥ 0.883, all P < 0.001), the cutoffs basically increased with age (from > 2.93 in 6-year-olds to > 3.07 in 18-year-olds among girls, and from > 2.96 in 6-year-olds to > 3.07 in 18-year-olds among boys). In addition, boys presented slightly larger cutoffs than girls in all ages except for 16 and 18 years old. For children aged 3-5 years, AL/CR ratio or AL combined with NCAR increased AUC to > 0.900.
conclusionAL/CR ratio provided the best prediction of myopia with age-dependent cutoff values for all but preschool children, and the cutoffs of boys were slightly larger than those of girls. For preschool children, AL/CR ratio or AL combined with NCAR is recommended to achieve satisfactory accuracy. AL/CR ratio calculated by two meridians showed similar predictive power but with different cutoffs.
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