Evidence map›Paper›PMID 37577676›Full record

ArticlebioRxiv : the preprint server for biology2023

An Integrated Platform for in vivo Electrophysiology in Spatial Cognition Experiments.

A Brea Guerrero, M Oijala, S C Moseley, T Tang, F Fletcher, Y Zheng, L M Sanchez, B J Clark, B L McNaughton, A A Wilber

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

A Brea GuerreroFlorida State University, Program in Neuroscience, Tallahassee, FL.
M OijalaUniv. of California, Irvine, Irvine, CA.
S C MoseleyPsychology Department, Florida State University, Tallahassee, FL.
T TangPsychology Department, Florida State University, Tallahassee, FL.
F FletcherPsychology Department, Florida State University, Tallahassee, FL.
Y ZhengFlorida State University, Program in Neuroscience, Tallahassee, FL.
L M SanchezDept. of Psychology, The University of New Mexico, Albuquerque, NM.
B J ClarkDept. of Psychology, The University of New Mexico, Albuquerque, NM.
B L McNaughtonUniv. of California, Irvine, Irvine, CA.
A A WilberFlorida State University, Program in Neuroscience, Tallahassee, FL.
Florida State University · USUniversity of New Mexico · USUniversity of California, Irvine · USUniversity of Lethbridge · CA

Funding

Hebb Marr Networks the Hippocampus and Spatial MemoryR37MH046823 · NIMH · UNIVERSITY OF LETHBRIDGE · PI MCNAUGHTON, BRUCE L · 2001 to 2010
$3.5M
Targeting the orexin pathway to treat sleep disorders and improve glymphatic clearance in Alzheimer’s diseaseR01AG070094 · NIA · FLORIDA STATE UNIVERSITY · PI WILBER, AARON A · 2021 to 2025
$2.4M
Neural Basis of Spatial Memory Deficits After Prenatal Alcohol ExposureR01AA029700 · NIAAA · UNIVERSITY OF NEW MEXICO · PI Benjamin J Clark · 2022 to 2026
$1.6M
Parietal-hippocampal network in the triple transgenic mouse model of AlzheimersR00AG049090 · NIA · FLORIDA STATE UNIVERSITY · PI WILBER, AARON A · 2017 to 2019
$747k
Parietal-hippocampal network in the triple transgenic mouse model of AlzheimersK99AG049090 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI WILBER, AARON A · 2015 to 2016
$189k
NETWORKS THE HIPPOCAMPUS AND SPATIAL MEMORYR01MH046823 · NIMH · UNIVERSITY OF ARIZONA · PI MCNAUGHTON, BRUCE L · 1990 to 2000
$179k
Phase sequences of posterior parietal cortex ensembles and sequence learningF32MH099682 · NIMH · UNIVERSITY OF CALIFORNIA-IRVINE · PI WILBER, AARON A · 2013 to 2013
$51k
NIAAA NIH HHS R01 AA029700NIA NIH HHS K99 AG049090NIA NIH HHS R00 AG049090NIA NIH HHS R01 AG070094NIMH NIH HHS F32 MH099682NIMH NIH HHS R01 MH046823NIMH NIH HHS R37 MH046823
6 · The paper itself

Abstract

Spatial cognition research requires behavioral paradigms that can distinguish between different navigational elements, such as allocentric (map-like) navigation and egocentric (e.g., body centered) navigation. To fill this need, we developed a flexible experimental platform that can be quickly modified without the need for significant changes to software and hardware. In this paper, we present this inexpensive and flexible behavioral platform paired with software which we are making freely available. Our behavioral platform serves as the foundation for a range of experiments, and though developed for assessing spatial cognition, it also has applications in the non-spatial domain of behavioral testing. There are two components of the software platform, 'Maze' and 'Stim Trigger'. Both programs can work in conjunction with electrophysiology acquisition systems, allowing for precise time stamping of neural events with behavior. The Maze program includes functionality for automatic reward delivery based on user defined zones. 'Stim Trigger' permits control of brain stimulation via any equipment that can be paired with an Arduino board. We seek to share our software and leverage the potential by expanding functionality in the future to meet the needs of a larger community of researchers.

Identifiers

PMID37577676
PMCPMC10418273
OpenAlexW4385606136

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.