Evidence map›Paper›PMID 37577480›Full record

ArticlebioRxiv : the preprint server for biology2023

A force-sensitive mutation reveals a spindle assembly checkpoint-independent role for dynein in anaphase progression.

David Salvador-Garcia, Li Jin, Andrew Hensley, Mert Gölcük, Emmanuel Gallaud, Sami Chaaban, Fillip Port, Alessio Vagnoni, Vicente José Planelles-Herrero, Mark A McClintock and 6 more

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 5 countries.

David Salvador-GarciaCell Biology Division, MRC Laboratory of Molecular Biology, Cambridge, CB2 0QH, UK.
Li JinCell Biology Division, MRC Laboratory of Molecular Biology, Cambridge, CB2 0QH, UK.
Andrew HensleyDepartment of Physics, University of California at Berkeley, Berkeley, CA 94720, USA.
Mert GölcükDepartment of Mechanical Engineering, Istanbul Technical University, Istanbul, 34437, Turkey.
Emmanuel GallaudInstitut de Génétique et Développement de Rennes - UMR 6290, Université de Rennes, F-35000 Rennes, France.
Sami ChaabanStructural Studies Division, MRC Laboratory of Molecular Biology, Cambridge, CB2 0QH, UK.
Fillip PortCell Biology Division, MRC Laboratory of Molecular Biology, Cambridge, CB2 0QH, UK.
Alessio VagnoniCell Biology Division, MRC Laboratory of Molecular Biology, Cambridge, CB2 0QH, UK.
Vicente José Planelles-HerreroCell Biology Division, MRC Laboratory of Molecular Biology, Cambridge, CB2 0QH, UK.
Mark A McClintockCell Biology Division, MRC Laboratory of Molecular Biology, Cambridge, CB2 0QH, UK.
Emmanuel DeriveryCell Biology Division, MRC Laboratory of Molecular Biology, Cambridge, CB2 0QH, UK.
Andrew P CarterStructural Studies Division, MRC Laboratory of Molecular Biology, Cambridge, CB2 0QH, UK.
Régis GietInstitut de Génétique et Développement de Rennes - UMR 6290, Université de Rennes, F-35000 Rennes, France.
Mert GürDepartment of Mechanical Engineering, Istanbul Technical University, Istanbul, 34437, Turkey.
Ahmet YildizDepartment of Physics, University of California at Berkeley, Berkeley, CA 94720, USA.
Simon L BullockCell Biology Division, MRC Laboratory of Molecular Biology, Cambridge, CB2 0QH, UK.
MRC Laboratory of Molecular Biology · GBInstitut de génétique et de développement de Rennes · FRUniversity of California, Berkeley · USIstanbul Technical University · TRUniversity of Pittsburgh · US

Funding

The Mechanism and Regulation of the Dynein Transport MachineryR35GM136414 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI Ahmet Yildiz · 2020 to 2026
$5.1M
Medical Research Council MC_U105178790Medical Research Council MC_UP_A025_1011National Centre for the Replacement, Refinement and Reduction of Animals in Research NC/N001753/1NIGMS NIH HHS R35 GM136414
6 · The paper itself

Abstract

The cytoplasmic dynein-1 (dynein) motor organizes cells by shaping microtubule networks and moving a large variety of cargoes along them. However, dynein's diverse roles complicate

Indexed as

axonal transportDrosophiladyneinforce productionkinetochoremicrotubule-binding domainmitosis

Identifiers

PMID37577480
PMCPMC10418259
OpenAlexW4385577762

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.