ReviewFrontiers in cellular and infection microbiology2023
Nitrofurantoin: properties and potential in treatment of urinary tract infection: a narrative review.
Review in Frontiers in cellular and infection microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
39 citing papers in PubMed, 61 citations in OpenAlex.
- Effect of human urinary microenvironment and fluid flow on antibiotic and phage therapy efficacy against uropathogenic Escherichia coli.Nature communications · 2026Article
- Conformational determinants of glucagon stability and aggregation kinetics in aqueous and commercial formulations.Protein science : a publication of the Protein Society · 2026Article
- UropathogenicAntibiotics (Basel, Switzerland) · 2026Review
- Medicinal Chemistry Perspectives on Drug Repurposing: Innovative Approaches and Therapeutic Breakthrough.Therapeutic innovation & regulatory science · 2026Review
- Nemonoxacin pharmacokinetics/pharmacodynamics againstAntimicrobial agents and chemotherapy · 2026Article
- From Access to Watch: An AWaRe-Oriented Evaluation of Antibiotic Prescribing in ASL Salerno.Antibiotics (Basel, Switzerland) · 2026Article
- One-Step Electrochemical Fabrication of Poly O-cresolphthalein Complexone and Electrochemically Reduced Graphene Oxide Modified Electrode for Detection of Nitrofurantoin.Sensors (Basel, Switzerland) · 2026Article
- Clinico-epidemiological determinants for empirical antibiotic prescriptions in suspected urinary tract infection cases attending peripheral hospitals of West Bengal, India- a cross sectional analysis.Scientific reports · 2026Article
- Comparative in vitro activity of furazidin and nitrofurantoin and assessment of resistance mechanisms in Escherichia coli isolates from urinary tract infections.Folia microbiologica · 2026Article
- Chronic uropathogenic Escherichia coli infections in adolescence: in vitro analysis of clinical isolates, multidrug resistance, and in vivo hippocampal cognitive impacts.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Recent trends in dual-acting hybrid antibiotics and combination therapies against Gram-negative pathogens.Journal of microbiology (Seoul, Korea) · 2026Review
- Evidentiary Standards for Newly Approved Antibiotics for Uncomplicated Urinary Tract Infections.Antibiotics (Basel, Switzerland) · 2026Article
- Optimizing urinary tract infection outcomes: nitrofurantoin versus fluoroquinolones.Bioinformation · 2026Article
- Phenyllactic Acid as a Marker of Antibiotic-Induced Metabolic Activity of Nosocomial Strains ofMicroorganisms · 2025Article
- Principles of bacteriostatic and bactericidal antibiotics at subinhibitory concentrations.mBio · 2025Article
- Nitrofurantoin resistance mechanisms in uropathogenic Escherichia coli isolates from Iran.Annals of clinical microbiology and antimicrobials · 2025Article
- Antimicrobial Prophylaxis for Recurrent Urinary Tract Infections in Premenopausal and Postmenopausal Women: A Retrospective Observational Study from an Outpatient Clinic in a Tertiary University Hospital.Antibiotics (Basel, Switzerland) · 2025Article
- Article
- Host niche-specific challenges hindering the treatment of polymicrobial infections.Journal of bacteriology · 2025Review
- Nitrofurantoin-Aminoglycoside Synergy Against Common Uropathogens Evaluated by Disc Diffusion: A Pilot Study.Microorganisms · 2025Article
Corrections and comments
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Authors and funding
9 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nitrofurantoin (NF), a wide-spectrum antibiotic accessible since 1953, is utilized widely to treat urinary tract infections as it usually stays active against drug-resistant uropathogen. The use of Nitrofurantoin has increased exponentially since new guidelines have repositioned it as first-line therapy for uncomplicated lower urinary tract infection (UTI). To, although fluoroquinolones are usually used to re-evaluate the first- and second-line therapies for treating uncomplicated UTI, their level of utilization is thought to be inappropriately excessive and will eventually have a detrimental impact; thus, we hypothesize that NF might be the best choice for this condition, because of its low frequency of utilization and its high susceptibility in common UTI pathogens. It can be concluded from this review that NF can be considered as the most effective drug in the treatment of acute urinary infection, but due to the long-term side effects of this drug, especially in elderly patients, it is essential to introduce some criteria for prescribing NF in cases of chronic UTI.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.