Evidence map›Paper›PMID 37577334›Full record

ArticleFrontiers in allergy2023

Characterization of the upper respiratory tract microbiota in Chilean asthmatic children reveals compositional, functional, and structural differences.

Ignacio Ramos-Tapia, Katiuska L Reynaldos-Grandón, Marcos Pérez-Losada, Eduardo Castro-Nallar

Abstract read
In one paragraph

Article in Frontiers in allergy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ignacio Ramos-TapiaCentro de Bioinformática y Biología Integrativa, Facultad de Ciencias de la Vida, Universidad Andrés Bello, Santiago, Chile.
Katiuska L Reynaldos-GrandónFacultad de Enfermería, Universidad Andrés Bello, Santiago, Chile.
Marcos Pérez-LosadaComputational Biology Institute, Department of Biostatistics and Bioinformatics, The George Washington University, Washington, DC, United States.
Eduardo Castro-NallarDepartamento de Microbiología, Facultad de Ciencias de la Salud, Universidad de Talca, Talca, Chile.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Around 155 million people worldwide suffer from asthma. In Chile, the prevalence of this disease in children is around 15% and has a high impact in the health system. Studies suggest that asthma is caused by multiple factors, including host genetics, antibiotic use, and the development of the airway microbiota. Here, we used 16S rRNA high-throughput sequencing to characterize the nasal and oral mucosae of 63 asthmatic and 89 healthy children (152 samples) from Santiago, Chile. We found that the nasal mucosa was dominated by a high abundance of

Indexed as

16S rRNAasthmaChilean microbiotanasal bacteriomeupper respiratory tract

Identifiers

PMID37577334
PMCPMC10419220

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.