Evidence map›Paper›PMID 37577070›Full record

ArticleThe European journal of psychiatry

High molar ratios of tumor necrosis factor

T I Morales, C E Stamper, L A Brenner

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The European journal of psychiatry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 83% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

T I MoralesVA Rocky Mountain Mental Illness Research, Education and Clinical Center, Aurora, CO 80045-8020, USA.
C E StamperVA Rocky Mountain Mental Illness Research, Education and Clinical Center, Aurora, CO 80045-8020, USA.
L A BrennerVA Rocky Mountain Mental Illness Research, Education and Clinical Center, Aurora, CO 80045-8020, USA.
Mental Illness Research, Education and Clinical Centers · US

Funding

Biological Signature and Safety of an Immunomodulatory Probiotic Intervention of Veterans with PTSDR01AT010005 · NCCIH · UNIVERSITY OF COLORADO DENVER · PI BRENNER, LISA A, LOWRY, CHRISTOPHER A · 2020 to 2025
$1.8M
Biological Signature and Safety of an Immunomodulatory Probiotic Intervention for Veterans with Co-Occuring Mild TBI and PTSDI21RX002232 · VA · VA EASTERN COLORADO HEALTH CARE SYSTEM · PI BRENNER, LISA A · 2016 to 2018
–
NCCIH NIH HHS R01 AT010005RRD VA I21 RX002232
6 · The paper itself

Abstract

Background and Objectives: Posttraumatic stress disorder (PTSD) and traumatic brain injury (TBI) are associated with chronic inflammation, as inferred from increased, but variable, peripheral levels of cytokines. We sought proof of concept for the notion that peripheral cytokine binding proteins and/or soluble receptors can confound measures of cytokines in those with a history of physical and psychological traumatic exposures. Efforts were focused on one of the major cytokines involved in inflammation, tumor necrosis factor- Methods: We examined blood plasma concentrations of TNF- Results: Molar concentrations of soluble TNFsRI and II exceeded concentrations of the TNF- Conclusions: TNF soluble receptors may bind to and sequester free TNF-

Indexed as

CytokinesInflammationMild traumatic brain injury (mTBI)NeuroinflammationPosttraumatic stress disorder (PTSD)Soluble tumor necrosis factor α receptors I and II (TNFsRI and TNFsRII)Tumor necrosis factor-α (TNF-α)

Identifiers

PMID37577070
PMCPMC10421642
OpenAlexW4377137315

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.