Evidence map›Paper›PMID 37576874›Full record

ArticleProceedings of machine learning research2022

Bias Aware Probabilistic Boolean Matrix Factorization.

Changlin Wan, Pengtao Dang, Tong Zhao, Yong Zang, Chi Zhang, Sha Cao

Abstract read
In one paragraph

Article in Proceedings of machine learning research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Changlin WanIndiana University, Indianapolis, Indiana, United States.
Pengtao DangIndiana University, Indianapolis, Indiana, United States.
Tong ZhaoAmazon, Seattle, Washington, United States.
Yong ZangIndiana University, Indianapolis, Indiana, United States.
Chi ZhangIndiana University, Indianapolis, Indiana, United States.
Sha CaoIndiana University, Indianapolis, Indiana, United States.

Funding

Tumor Microenvironment and Metastasis ProgramP30CA082709 · NCI · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI Sara K Quinney · 1999 to 2026
$59.3M
Research Education ComponentP30AG072976 · NIA · INDIANA UNIVERSITY INDIANAPOLIS · PI ANDREW J SAYKIN · 2021 to 2026
$24.1M
Construction of cell specific gene co-regulations signatures based on single cell transcriptomics analysisR01GM131399 · NIGMS · SOUTH DAKOTA STATE UNIVERSITY · PI MA, QIN · 2018 to 2021
$1.3M
NCI NIH HHS P30 CA082709NIA NIH HHS P30 AG072976NIGMS NIH HHS R01 GM131399
6 · The paper itself

Abstract

Boolean matrix factorization (BMF) is a combinatorial problem arising from a wide range of applications including recommendation system, collaborative filtering, and dimensionality reduction. Currently, the noise model of existing BMF methods is often assumed to be homoscedastic; however, in real world data scenarios, the deviations of observed data from their true values are almost surely diverse due to stochastic noises, making each data point not equally suitable for fitting a model. In this case, it is not ideal to treat all data points as equally distributed. Motivated by such observations, we introduce a probabilistic BMF model that recognizes the object- and feature-wise bias distribution respectively, called bias aware BMF (BABF). To the best of our knowledge, BABF is the first approach for Boolean decomposition with consideration of the feature-wise and object-wise bias in binary data. We conducted experiments on datasets with different levels of background noise, bias level, and sizes of the signal patterns, to test the effectiveness of our method in various scenarios. We demonstrated that our model outperforms the state-of-the-art factorization methods in both accuracy and efficiency in recovering the original datasets, and the inferred bias level is highly significantly correlated with true existing bias in both simulated and real world datasets.

Identifiers

PMID37576874
PMCPMC10421704

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.