Evidence map›Paper›PMID 37576639›Full record

ReviewACS omega2023

Nanoadjuvants: Promising Bioinspired and Biomimetic Approaches in Vaccine Innovation.

Dhruv N Desai, Ahmed Mahal, Rajat Varshney, Ahmad J Obaidullah, Bhawna Gupta, Pratikhya Mohanty, Priyabrata Pattnaik, Nrusingha Charan Mohapatra, Snehasish Mishra, Venkataramana Kandi and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in ACS omega, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 5 countries.

Dhruv N DesaiDepartment of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.
Ahmed MahalDepartment of Medical Biochemical Analysis, College of Health Technology, Cihan University-Erbil, Erbil, Kurdistan Region, Iraq.ORCID https://orcid.org/0000-0002-6977-3752
Rajat VarshneyDepartment of Veterinary Microbiology, FVAS, Banaras Hindu University, Mirzapur 231001, India.
Ahmad J ObaidullahDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
Bhawna GuptaSchool of Biotechnology, KIIT Deemed-to-be University, Bhubaneswar 751024, Odisha, India.
Pratikhya MohantyBioenergy Lab, BDTC, School of Biotechnology, KIIT Deemed-to-be University, Bhubaneswar 751024, Odisha, India.
Priyabrata PattnaikIndian Immunological Ltd., Gachibowli, Hyderabad 500032, India.
Nrusingha Charan MohapatraProcess Analytical Division, Vaxxinity Inc, Merrit Island, Florida 32953, United States.
Snehasish MishraBioenergy Lab, BDTC, School of Biotechnology, KIIT Deemed-to-be University, Bhubaneswar 751024, Odisha, India.
Venkataramana KandiDepartment of Microbiology, Prathima Institute of Medical Sciences, Karimnagar 505 417, Telangana, India.
Ali A RabaanMolecular Diagnostic Laboratory, Johns Hopkins Aramco Healthcare, Dhahran 31311, Saudi Arabia.
Ranjan K MohapatraDepartment of Chemistry, Government College of Engineering, Keonjhar 758002, Odisha, India.ORCID https://orcid.org/0000-0001-7623-3343
KIIT University · INAlfaisal University · SABanaras Hindu University · INCihan University-Erbil · IQGovernment College of Engineering, Keonjhar · INIndian Immunologicals (India) · INInstitute of Medical Sciences · INKing Saud University · SAUniversity of Pennsylvania · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adjuvants are the important part of vaccine manufacturing as they elicit the vaccination effect and enhance the durability of the immune response through controlled release. In light of this, nanoadjuvants have shown unique broad spectrum advantages. As nanoparticles (NPs) based vaccines are fast-acting and better in terms of safety and usability parameters as compared to traditional vaccines, they have attracted the attention of researchers. A vaccine nanocarrier is another interesting and promising area for the development of next-generation vaccines for prophylaxis. This review looks at the various nanoadjuvants and their structure-function relationships. It compiles the state-of-art literature on numerous nanoadjuvants to help domain researchers orient their understanding and extend their endeavors in vaccines research and development.

Identifiers

PMID37576639
PMCPMC10413842
OpenAlexW4385225033

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.