Evidence map›Paper›PMID 37576624›Full record

ArticleACS omega2023

Exploration of Remarkably Potential Multitarget-Directed N-Alkylated-2-(substituted phenyl)-1

Ngoc-Kim-Ngan Phan, Thi-Kim-Chi Huynh, Hoang-Phuc Nguyen, Quoc-Tuan Le, Thi-Cam-Thu Nguyen, Kim-Khanh-Huy Ngo, Thi-Hong-An Nguyen, Khoa Anh Ton, Khac-Minh Thai, Thi-Kim-Dung Hoang

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Review of promising benzimidazole-based anticancer agents (2023-2026).Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2026
    Review
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  7. Review
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  9. Article
  10. Inhibition of Shikimate Kinase from Methicillin-ResistantInternational journal of molecular sciences · 2024
    Article
  11. Isolation and Identification of Chemical Compounds fromMolecules (Basel, Switzerland) · 2023
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Ngoc-Kim-Ngan PhanInstitute of Chemical Technology, Vietnam Academy of Science and Technology, No.1A, TL29 Str., Thanh Loc Ward, Dist. 12, Ho Chi Minh City 70000, Vietnam.ORCID https://orcid.org/0000-0003-1637-0535
Thi-Kim-Chi HuynhInstitute of Chemical Technology, Vietnam Academy of Science and Technology, No.1A, TL29 Str., Thanh Loc Ward, Dist. 12, Ho Chi Minh City 70000, Vietnam.ORCID https://orcid.org/0000-0002-6214-8022
Hoang-Phuc NguyenInstitute of Chemical Technology, Vietnam Academy of Science and Technology, No.1A, TL29 Str., Thanh Loc Ward, Dist. 12, Ho Chi Minh City 70000, Vietnam.
Quoc-Tuan LeInstitute of Chemical Technology, Vietnam Academy of Science and Technology, No.1A, TL29 Str., Thanh Loc Ward, Dist. 12, Ho Chi Minh City 70000, Vietnam.ORCID https://orcid.org/0009-0007-3073-7520
Thi-Cam-Thu NguyenInstitute of Chemical Technology, Vietnam Academy of Science and Technology, No.1A, TL29 Str., Thanh Loc Ward, Dist. 12, Ho Chi Minh City 70000, Vietnam.ORCID https://orcid.org/0000-0001-5458-8012
Kim-Khanh-Huy NgoInstitute of Chemical Technology, Vietnam Academy of Science and Technology, No.1A, TL29 Str., Thanh Loc Ward, Dist. 12, Ho Chi Minh City 70000, Vietnam.
Thi-Hong-An NguyenInstitute of Chemical Technology, Vietnam Academy of Science and Technology, No.1A, TL29 Str., Thanh Loc Ward, Dist. 12, Ho Chi Minh City 70000, Vietnam.
Khoa Anh TonInstitute of Chemical Technology, Vietnam Academy of Science and Technology, No.1A, TL29 Str., Thanh Loc Ward, Dist. 12, Ho Chi Minh City 70000, Vietnam.
Khac-Minh ThaiDepartment of Medicinal Chemistry, Faculty of Pharmacy, University of Medicine and Pharmacy at Ho Chi Minh City, No.41-43, Dinh Tien Hoang Str., Dist. 1, Ho Chi Minh City 70000, Vietnam.ORCID https://orcid.org/0000-0002-5279-9614
Thi-Kim-Dung HoangInstitute of Chemical Technology, Vietnam Academy of Science and Technology, No.1A, TL29 Str., Thanh Loc Ward, Dist. 12, Ho Chi Minh City 70000, Vietnam.ORCID https://orcid.org/0000-0002-9369-8051
Vietnam Academy of Science and Technology · VNUniversity of Medicine and Pharmacy at Ho Chi Minh City · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Improving lipophilicity for drugs to penetrate the lipid membrane and decreasing bacterial and fungal coinfections for patients with cancer pose challenges in the drug development process. Here, a series of new N-alkylated-2-(substituted phenyl)-1

Identifiers

PMID37576624
PMCPMC10413844
OpenAlexW4385342161

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.