Evidence map›Paper›PMID 37576098›Full record

ArticleJournal of medical physics

Multiple Brain Metastases Radiosurgery with CyberKnife Device: Dosimetric Comparison between Fixed/Iris and Multileaf Collimator Plans.

Anna Ianiro, Erminia Infusino, Marco D'Andrea, Laura Marucci, Alessia Farneti, Francesca Sperati, Bartolomeo Cassano, Sara Ungania, Antonella Soriani

Open access · diamondAbstract read
In one paragraph

Article in Journal of medical physics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Anna IaniroDepartment of Medical Physics, IRCCS Regina Elena National Cancer Institute - IFO, Rome, Italy.
Erminia InfusinoDepartment of Medical Physics, IRCCS Regina Elena National Cancer Institute - IFO, Rome, Italy.
Marco D'AndreaDepartment of Medical Physics, IRCCS Regina Elena National Cancer Institute - IFO, Rome, Italy.
Laura MarucciDepartment of Radiation Oncology, IRCCS Regina Elena National Cancer Institute - IFO, Rome, Italy.
Alessia FarnetiDepartment of Radiation Oncology, IRCCS Regina Elena National Cancer Institute - IFO, Rome, Italy.
Francesca SperatiDepartment of Biostatistics and Bioinformatics, Clinical Trial Center, IRCCS San Gallicano Dermatological Institute - IFO, Rome, Italy.
Bartolomeo CassanoDepartment of Medical Physics, IRCCS Regina Elena National Cancer Institute - IFO, Rome, Italy.
Sara UnganiaDepartment of Medical Physics, IRCCS Regina Elena National Cancer Institute - IFO, Rome, Italy.
Antonella SorianiDepartment of Medical Physics, IRCCS Regina Elena National Cancer Institute - IFO, Rome, Italy.
Istituti di Ricovero e Cura a Carattere Scientifico · ITIstituti Fisioterapici Ospitalieri · ITSan Gallicano Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: In our institution, stereotactic radiosurgery of multiple brain metastases is performed with the CyberKnife® (CK) device, using fixed/Iris collimators. In this study, nineteen fixed/Iris plans were recalculated with the multileaf collimator (MLC), to assess if it is possible to produce plans with comparable dosimetric overall quality. Materials and Methods: For consistent comparisons, MLC plans were re-optimized and re-normalized in order to achieve the same minimum dose for the total planning target volume (PTV Results: The reoptimized plans were reviewed by the radiation oncologist and were found clinically acceptable according to the The American Association of Physicists in Medicine (AAPM) Task Group-101 protocol. However, fixed/Iris plans provided significantly higher CN (+8.6%), HI (+2.2%), and DGI (+44.0%) values, and significantly lower ID values (-35.9%). For PTV Conclusions: CK-MLC plans for the stereotactic treatment of brain multi metastases could provide an important advantage in terms of treatment duration. However, to contain the increased risk for brain radionecrosis, it could be useful to calculate MLC plans only for patients with large PTV

Indexed as

Brain radiosurgeryCyberKnife®dosimetric comparison

Identifiers

PMID37576098
PMCPMC10419749
OpenAlexW4385798593

What OpenQuestion holds

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LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.