Evidence map›Paper›PMID 37575384›Full record

ArticleBio-protocol2023

Binging from Food to Alcohol: A Sequential Interaction Between Binging Behaviors in Male Wistar Rats.

Sergio Cuesta-Martínez, Leandro Ruiz-Leyva, Ana María Jiménez-García, Teresa Aparicio-Mescua, Olga López-Guarnido, Ricardo Marcos Pautassi, Ignacio Morón, Cruz Miguel Cendán

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bio-protocol, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 85% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Sergio Cuesta-MartínezDepartment of Pharmacology, Biomedical Research Center (CIBM) and Institute of Neuroscience, Faculty of Medicine, University of Granada, Parque Tecnológico de Ciencias de la Salud, 18016, Granada, Spain.
Leandro Ruiz-LeyvaDepartment of Pharmacology, Biomedical Research Center (CIBM) and Institute of Neuroscience, Faculty of Medicine, University of Granada, Parque Tecnológico de Ciencias de la Salud, 18016, Granada, Spain.
Ana María Jiménez-GarcíaDepartment of Psychology, Faculty of Life Sciences and Nature, University of Nebrija, Hoyo de Manzanares, 28240, Madrid, Spain.
Teresa Aparicio-MescuaDepartment of Psychobiology and Centre of Investigation of Mind, Brain, and Behavior (CIMCYC), Faculty of Psychology, University of Granada, Campus Cartuja, 18071, Granada, Spain.
Olga López-GuarnidoDepartment of Legal Medicine and Toxicology, Faculty of Medicine, University of Granada, Parque Tecnológico de Ciencias de la Salud, 18016, Granada, Spain.
Ricardo Marcos PautassiInstituto de Investigación Médica M. y M. Ferreyra (INIMEC - CONICET-Universidad Nacional de Córdoba), Córdoba, 5000, Argentina, Faculty of Psychology, UNC, Córdoba, Argentina.
Ignacio MorónDepartment of Psychobiology and Centre of Investigation of Mind, Brain, and Behavior (CIMCYC), Faculty of Psychology, University of Granada, Campus Cartuja, 18071, Granada, Spain.
Cruz Miguel CendánDepartment of Pharmacology, Biomedical Research Center (CIBM) and Institute of Neuroscience, Faculty of Medicine, University of Granada, Parque Tecnológico de Ciencias de la Salud, 18016, Granada, Spain.
Parque Tecnológico de la Salud · ESUniversidad de Granada · ESConsejo Nacional de Investigaciones Científicas y Técnicas · ARUniversidad Nebrija · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of excessive alcohol (ethanol) and/or highly palatable food self-administration is an essential task to elucidate the neurobiological mechanisms that underlie these behaviors. Previous work has highlighted that ethanol self-administration is modulated by both the induction of aversive states (i.e., stress or frustration) and by the concurrent availability of appetitive stimuli (e.g., food). In our protocol, rats are food deprived for three days until they reach 82%-85% of their ad libitum weight. After that, rats are exposed daily for 10 days to a brief binge or control eating experience with highly sugary and palatable food (i.e., the ingestion of 11.66 and 0.97 kcal/3 min, respectively), which is followed by a two-bottle-choice test (ethanol vs. water) in their home cages for 90 min. This model induces robust binge eating, which is followed by a selective increase in ethanol self-administration. Therefore, this protocol allows to study: a) behavioral and neurobiological factors related to binge eating, b) different stages of alcohol use, and c) interactions between the latter and other addictive-like behaviors, like binge eating.

Indexed as

AddictionAlcoholBinge drinkingBinge eatingTwo-bottle-choice testWistar rats

Identifiers

PMID37575384
PMCPMC10415202
OpenAlexW4385608714

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.