Evidence map›Paper›PMID 37575226›Full record

Trial reportFrontiers in immunology2023

Orally administrated

Fengyuan Qi, Shangrong Fan, Chao Fang, Lan Ge, Jinli Lyu, Zhuoqi Huang, Shaowei Zhao, Yuanqiang Zou, Liting Huang, Xinyang Liu and 6 more

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04771728 (Department of Obstetrics and Gynecology, Peking University Shenzhen Hospital), which is not on this map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04771728 phase4recruitingnot on this map

Department of Obstetrics and Gynecology, Peking University Shenzhen Hospital

TypeinterventionalSponsorPeking University Shenzhen HospitalRan2020 to 2026Enrolled140ConditionsBacterial VaginosisArmsMetronidazole vaginal suppositories, Metronidazole vaginal suppositories and Probiotics(Umeta-mimi)
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Microbiology spectrum · 2025
    Trial
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Orally ingestedFrontiers in microbiology · 2026
    Article
  9. Review
  10. Article
  11. Review
  12. The activity of cell-free supernatant ofFrontiers in cellular and infection microbiology · 2025
    Article
  13. Article
  14. Article
  15. Review
  16. Microorganisms · 2024
    Article
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 2 countries.

Fengyuan QiDepartment of Obstetrics and Gynecology, Peking University Shenzhen Hospital, Shenzhen, China.
Shangrong FanDepartment of Obstetrics and Gynecology, Peking University Shenzhen Hospital, Shenzhen, China.
Chao FangBGI-Shenzhen, Shenzhen, China.
Lan GeBGI Precision Nutrition (Shenzhen) Technology Co., Ltd, Shenzhen, China.
Jinli LyuDepartment of Obstetrics and Gynecology, Peking University Shenzhen Hospital, Shenzhen, China.
Zhuoqi HuangBGI-Shenzhen, Shenzhen, China.
Shaowei ZhaoBGI-Shenzhen, Shenzhen, China.
Yuanqiang ZouBGI-Shenzhen, Shenzhen, China.
Liting HuangDepartment of Obstetrics and Gynecology, Peking University Shenzhen Hospital, Shenzhen, China.
Xinyang LiuDepartment of Obstetrics and Gynecology, Peking University Shenzhen Hospital, Shenzhen, China.
Yiheng LiangDepartment of Obstetrics and Gynecology, Peking University Shenzhen Hospital, Shenzhen, China.
Yongke ZhangDepartment of Obstetrics and Gynecology, Peking University Shenzhen Hospital, Shenzhen, China.
Yiyi ZhongBGI Precision Nutrition (Shenzhen) Technology Co., Ltd, Shenzhen, China.
Haifeng ZhangBGI Precision Nutrition (Shenzhen) Technology Co., Ltd, Shenzhen, China.
Liang XiaoBGI-Shenzhen, Shenzhen, China.
Xiaowei ZhangDepartment of Obstetrics and Gynecology, Peking University Shenzhen Hospital, Shenzhen, China.
Hong Kong University of Science and Technology · HKBGI Group (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial vaginosis (BV) is a common infection of the lower genital tract with a vaginal microbiome dysbiosis caused by decreasing of lactobacilli. Previous studies suggested that supplementation with live Clinical trial registration: https://classic.clinicaltrials.gov/ct2/show/, identifier NCT04771728.

Indexed as

Lactobacillus crispatusLactobacillus gasseriVaginosis, BacterialAdjuvants, ImmunologicAdjuvants, PharmaceuticFemaleHumansLactobacillusMetronidazoleTreatment OutcomeVaginaAdjuvants, ImmunologicAdjuvants, PharmaceuticMetronidazolebacterial vaginosisLactobacillusoral administrationPrevotella timonensisvaginal microbiome

Identifiers

PMID37575226
PMCPMC10415204
OpenAlexW4385296637

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.