Evidence map›Paper›PMID 37575176›Full record

ArticleESCAPE. European Symposium on Computer Aided Process Engineering2023

Binary Classification of the Endocrine Disrupting Chemicals by Artificial Neural Networks.

Zahir Aghayev, George F Walker, Funda Iseri, Moustafa Ali, Adam T Szafran, Fabio Stossi, Michael A Mancini, Efstratios N Pistikopoulos, Burcu Beykal

Open access · greenAbstract read
In one paragraph

Article in ESCAPE. European Symposium on Computer Aided Process Engineering, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Zahir AghayevDepartment of Chemical and Biomolecular Engineering, University of Connecticut, Storrs, CT 06269, USA.
George F WalkerDepartment of Chemical and Biomolecular Engineering, University of Connecticut, Storrs, CT 06269, USA.
Funda IseriArtie McFerrin Department of Chemical Engineering, Texas A&M University, College Station, TX 77843, USA.
Moustafa AliArtie McFerrin Department of Chemical Engineering, Texas A&M University, College Station, TX 77843, USA.
Adam T SzafranMolecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA.
Fabio StossiMolecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA.
Michael A ManciniMolecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA.
Efstratios N PistikopoulosArtie McFerrin Department of Chemical Engineering, Texas A&M University, College Station, TX 77843, USA.
Burcu BeykalDepartment of Chemical and Biomolecular Engineering, University of Connecticut, Storrs, CT 06269, USA.
Baylor College of Medicine · USTexas A&M University · USUniversity of Connecticut · USClean Energy (United States) · US

Funding

Single cell, multi-parametric high throughput platform to classify endocrine disruptor potential of mixturesP42ES027704 · NIEHS · TEXAS A&M UNIVERSITY · PI Efstratios Pistikopoulos · 2017 to 2026
$21.2M
NIEHS NIH HHS P42 ES027704
6 · The paper itself

Abstract

We develop a machine learning framework that integrates high content/high throughput image analysis and artificial neural networks (ANNs) to model the separation between chemical compounds based on their estrogenic receptor activity. Natural and man-made chemicals have the potential to disrupt the endocrine system by interfering with hormone actions in people and wildlife. Although numerous studies have revealed new knowledge on the mechanism through which these compounds interfere with various hormone receptors, it is still a very challenging task to comprehensively evaluate the endocrine disrupting potential of all existing chemicals and their mixtures by pure

Indexed as

artificial neural networksestrogenic potentialhigh throughput analysismachine learningnonlinear classification

Identifiers

PMID37575176
PMCPMC10413412
OpenAlexW4384789428

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.