ArticleJournal of Parkinson's disease2023
Freezing of Gait in Parkinson's Disease: Implications for Dual-Task Walking.
Article in Journal of Parkinson's disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- Telerehabilitation for Parkinson's disease: a systematic review and meta-analysis based on randomized controlled trials.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Pooled it
- The Effects of Anxiety and Cognitive Load on Freezing of Gait in Parkinson's Disease.The European journal of neuroscience · 2026Article
- Freezing of Gait Levodopa Response Pattern in Parkinson's Disease Provides Clues to Pathophysiology.The European journal of neuroscience · 2026Review
- Discriminating vascular parkinsonism from early-stage postural instability gait difficulty subtype dominant Parkinson's disease: a dual-task gait analysis using wearable sensors.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
- Dual-task gait and gait-cognition coupling in patients with Parkinson's disease versus healthy older adults: moderation by cognitive status.Frontiers in aging neuroscience · 2026Article
- Neuromodulation of Cortical Targets in Freezing of Gait.The European journal of neuroscience · 2026Review
- The relationship between white matter hyperintensity and gait in patients with cerebral small vessel disease.Frontiers in neurology · 2026Article
- L-Dopa Comparably Improves Gait and Limb Movements in Parkinson's Disease: A Wearable Sensor Analysis.Biomedicines · 2025Article
- Theta-frequency subthalamic stimulation enhances conflict resolution in Parkinson's disease patients with freezing of gait through frontal cortex modulation.NPJ Parkinson's disease · 2025Article
- Management of freezing of gait - mechanism-based practical recommendations.Nature reviews. Neurology · 2025Review
- Detecting Freezing of Gait in Parkinson Disease Using Multiple Wearable Sensors Sets During Various Walking Tasks Relative to Medication Conditions (DetectFoG): Protocol for a Prospective Cohort Study.JMIR research protocols · 2025Article
- A framework to standardize gait study protocols in Parkinson's disease.Journal of Parkinson's disease · 2025Article
- Knowledge mapping of freezing of gait in Parkinson's disease: a bibliometric analysis.Frontiers in neuroscience · 2024Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundThe simultaneous completion of multiple tasks (dual-tasking, DT) often leads to poorer task performance (DT cost, DTC). People with Parkinson's disease (PwPD) exhibit difficulty with DT, and DTC may be particularly pronounced in PwPD with freezing of gait (FOG).
objectiveThis study assessed the relationship between FOG status and DTC during gait.
methodsGait parameters were collected using inertial sensors in 106 PwPD (off-medication), including definite-freezers (dFOG; n = 25), possible-freezers (pFOG; n = 16), and non-freezers (nFOG; n = 65) during single (ST)-and DT walking.
resultsPwPD with dFOG had larger (worse) DTC than nFOG for foot-strike angle, stride length, toe-off angle, variability of foot-strike angle, and arm range of motion (ROM). After accounting for covariates, DTC for toe-off angle and stride length remained worse in PwPD who freeze. Worse cognition predicted larger DTC for stride length, gait cycle duration, gait speed, and step duration across groups. Men had larger DTC compared to women for gait speed, variability in foot-strike angle, stride length, and arm ROM. Increased variability in gait speed DTC was associated with increased disease severity.
conclusionThese findings provide additional support that PwPD who freeze may rely on greater cortical control for the execution of specific gait metrics. The results also underscore the importance of considering cognition when assessing DT ability in PwPD.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.