Evidence map›Paper›PMID 37573421›Full record

ArticleTrials2023

A technology-enabled multi-disciplinary team-based care model for the management of Long COVID and other fatiguing illnesses within a federally qualified health center: protocol for a two-arm, single-blind, pragmatic, quality improvement professional cluster randomized controlled trial.

Job G Godino, Jane C Samaniego, Sydney P Sharp, Douglas Taren, Alexandra Zuber, Amy J Armistad, Amanda M Dezan, Azure J Leyba, Janna L Friedly, Aaron E Bunnell and 9 more

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05167227 (The Long COVID and Fatiguing Illness Recovery Program - A Pragmatic, Quality Improvement, Professional Cluster, Randomized Controlled Trial.), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05167227 naactive not recruitingnot on this map

The Long COVID and Fatiguing Illness Recovery Program - A Pragmatic, Quality Improvement, Professional Cluster, Randomized Controlled Trial.

TypeinterventionalSponsorFamily Health Centers of San DiegoRan2021 to 2025Enrolled20ConditionsSARS-CoV-2 Acute Respiratory Disease, Myalgic Encephalomyelitis, Chronic Fatigue Syndrome, Post-acute Sequelae of SARS-COV-2 InfectionArmsExtension for Community Healthcare Outcomes
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 8 institutions in 1 country.

Job G GodinoLaura Rodriguez Research Institute, Family Health Centers of San Diego, 1750 5Th Ave, San Diego, CA, 92101, USA. jobg@fhcsd.org.ORCID http://orcid.org/0000-0002-4852-6277
Jane C SamaniegoLaura Rodriguez Research Institute, Family Health Centers of San Diego, 1750 5Th Ave, San Diego, CA, 92101, USA.
Sydney P SharpLaura Rodriguez Research Institute, Family Health Centers of San Diego, 1750 5Th Ave, San Diego, CA, 92101, USA.
Douglas TarenDepartment of Pediatrics and Nutrition, University of Colorado, 13001 East 17Th Place, Aurora, CO, 80045, USA.
Alexandra ZuberAta Health Strategies, LLC, 1537 D Street NE, Washington, DC, 20002, USA.
Amy J ArmistadProject ECHO, University of New Mexico Health Sciences Center, 1650 University Blvd NE, Albuquerque, NM, 87102, USA.
Amanda M DezanProject ECHO, University of New Mexico Health Sciences Center, 1650 University Blvd NE, Albuquerque, NM, 87102, USA.
Azure J LeybaProject ECHO, University of New Mexico Health Sciences Center, 1650 University Blvd NE, Albuquerque, NM, 87102, USA.
Janna L FriedlyDepartment of Medicine, University of Washington, 1959 NE Pacific St, Seattle, WA, 98195, USA.
Aaron E BunnellDepartment of Medicine, University of Washington, 1959 NE Pacific St, Seattle, WA, 98195, USA.
Eva MatthewsLaura Rodriguez Research Institute, Family Health Centers of San Diego, 1750 5Th Ave, San Diego, CA, 92101, USA.
Maureen J MillerNational Center for Emerging and Zoonotic Infectious Diseases, U.S. Centers for Disease Control and Prevention, 1600 Clifton Rd, Atlanta, GA, 30333, USA.
Elizabeth R UngerNational Center for Emerging and Zoonotic Infectious Diseases, U.S. Centers for Disease Control and Prevention, 1600 Clifton Rd, Atlanta, GA, 30333, USA.
Jeanne BertolliNational Center for Emerging and Zoonotic Infectious Diseases, U.S. Centers for Disease Control and Prevention, 1600 Clifton Rd, Atlanta, GA, 30333, USA.
Alison HinckleyNational Center for Emerging and Zoonotic Infectious Diseases, U.S. Centers for Disease Control and Prevention, 1600 Clifton Rd, Atlanta, GA, 30333, USA.
Jin-Mann S LinNational Center for Emerging and Zoonotic Infectious Diseases, U.S. Centers for Disease Control and Prevention, 1600 Clifton Rd, Atlanta, GA, 30333, USA.
John D ScottDepartment of Medicine, University of Washington, 1959 NE Pacific St, Seattle, WA, 98195, USA.
Bruce B StrumingerProject ECHO, University of New Mexico Health Sciences Center, 1650 University Blvd NE, Albuquerque, NM, 87102, USA.
Christian RamersLaura Rodriguez Research Institute, Family Health Centers of San Diego, 1750 5Th Ave, San Diego, CA, 92101, USA.
Centers for Disease Control and Prevention · USUniversity of New Mexico · USUniversity of Washington · USFamily Health Centers of San Diego · USSan Diego State University · USUC San Diego Health System · USUniversity of California San Diego · USUniversity of Colorado Denver · US

Funding

CDC HHS 75D30121C11341
6 · The paper itself

Abstract

backgroundThe clinical burden of Long COVID, myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), and other post-infectious fatiguing illnesses (PIFI) is increasing. There is a critical need to advance understanding of the effectiveness and sustainability of innovative approaches to clinical care of patients having these conditions.

methodsWe aim to assess the effectiveness of a Long COVID and Fatiguing Illness Recovery Program (LC&FIRP) in a two-arm, single-blind, pragmatic, quality improvement, professional cluster, randomized controlled trial in which 20 consenting clinicians across primary care clinics in a Federally Qualified Health Center system in San Diego, CA, will be randomized at a ratio of 1:1 to either participate in (1) weekly multi-disciplinary team-based case consultation and peer-to-peer sharing of emerging best practices (i.e., teleECHO (Extension for Community Healthcare Outcomes)) with monthly interactive webinars and quarterly short courses or (2) monthly interactive webinars and quarterly short courses alone (a control group); 856 patients will be assigned to participating clinicians (42 patients per clinician). Patient outcomes will be evaluated according to the study arm of their respective clinicians. Quantitative and qualitative outcomes will be measured at 3- and 6-months post-baseline for clinicians and every 3-months post assignment to a participating clinician for patients. The primary patient outcome is change in physical function measured using the Patient-Reported Outcomes Measurement Information System (PROMIS)-29. Analyses of differences in outcomes at both the patient and clinician levels will include a linear mixed model to compare change in outcomes from baseline to each post-baseline assessment between the randomized study arms. A concurrent prospective cohort study will compare the LC&FIRP patient population to the population enrolled in a university health system. Longitudinal data analysis approaches will allow us to examine differences in outcomes between cohorts. DISCUSSION: We hypothesize that weekly teleECHO sessions with monthly interactive webinars and quarterly short courses will significantly improve clinician- and patient-level outcomes compared to the control group. This study will provide much needed evidence on the effectiveness of a technology-enabled multi-disciplinary team-based care model for the management of Long COVID, ME/CFS, and other PIFI within a federally qualified health center.

trial registrationClinicalTrials.gov, NCT05167227 . Registered on December 22, 2021.

Indexed as

COVID-19Fatigue Syndrome, ChronicHumansMuscle FatiguePost-Acute COVID-19 SyndromePragmatic Clinical Trials as TopicProspective StudiesQuality ImprovementRandomized Controlled Trials as TopicSARS-CoV-2Single-Blind MethodChronic fatigue syndrome (CFS)Long COVIDMyalgic encephalomyelitis (ME)Post COVID-19 conditions (PCC)Post-infectious fatiguing illnesses (PIFI)

Identifiers

PMID37573421
PMCPMC10423413
OpenAlexW4385774171

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.