ArticlePediatric research2023
Neonatal encephalopathy and hypoxic-ischemic encephalopathy: moving from controversy to consensus definitions and subclassification.
Abstract readEditorial
In one paragraph
Article in Pediatric research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 4 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 4 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Systematic review of terminology, definitions, and eligibility criteria in trials of neonatal encephalopathy, hypoxic-ischemic encephalopathy, and perinatal asphyxia.Pediatric research · 2026Pooled it
- MRI scoring systems in neonatal encephalopathy and neurodevelopmental outcomes: a systematic review.Journal of perinatology : official journal of the California Perinatal Association · 2026Pooled it
- Melatonin treatment for neonatal encephalopathy.The Cochrane database of systematic reviews · 2026Pooled it
- Neonatal encephalopathy multiorgan scoring systems: systematic review.Frontiers in pediatrics · 2024Pooled it
- Temporal profile of serum orexin-A in neonatal hypoxic-ischemic encephalopathy: a prospective longitudinal study.BMC pediatrics · 2026Observational
- Beyond definitions: measuring severity in neonatal encephalopathy.Pediatric research · 2026Article
- Engaging families with experience of neonatal hypoxic ischemic encephalopathy: a call to action.Pediatric research · 2026Review
- Neonatal encephalopathy mortality rate in Aotearoa, New Zealand: review of national data 2010-2020.BMJ paediatrics open · 2026Article
- Early neurological and developmental trajectories of infants at high risk of cerebral palsy in Bangladesh: a prospective longitudinal cohort study.BMJ paediatrics open · 2026Article
- Current Practices in Hyperglycemia Management in Neonatal Encephalopathy: A Treatment of Hyperglycemia in Neonatal Encephalopathy (THiNE) Consortium Study.American journal of perinatology · 2026Article
- Diffusion tensor imaging and MR spectroscopy in the evaluation of neonatal encephalopathies.Journal of neonatal-perinatal medicine · 2026Article
- Machine learning based classification in obstetrics: evaluating models, partitioning strategies, and key predictors in cardiotocography.BMC pregnancy and childbirth · 2026Article
- Basilar artery flow velocities and optic nerve sheath diameter as adjuvant tools for early diagnosis of hypoxic ischemic encephalopathy in neonates.Italian journal of pediatrics · 2026Article
- Is there a role for apolipoprotein E in perinatal brain injury?Molecular and cellular pediatrics · 2026Review
- Biomarkers in neonatal encephalopathy: the role of high-mobility group box 1 in prognosis and potential therapy.Pediatric research · 2026Article
- Ultrafast ultrasound imaging reveals altered cerebral blood flow in newborn rats with hypoxic-ischemic encephalopathy.Pediatric research · 2026Article
- Beyond hypoxic-ischemic encephalopathy: genetic insights and precision diagnosis in neonatal encephalopathies.Frontiers in medicine · 2026Review
- AI-Driven Quantitative Metabolomics for Early and Precise HIE Diagnosis: Challenges and Solutions.ACS omega · 2025Review
- An epigenetic perspective on neonatal encephalopathy with suspected hypoxic ischaemic encephalopathy.Clinical epigenetics · 2025Review
- Multi-organ dysfunction across the neonatal encephalopathy spectrum.Pediatric research · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
30 authors.
Eleanor J MolloyDiscipline of Paediatrics, Trinity College Dublin, the University of Dublin, Dublin, Ireland. Eleanor.molloy@tcd.ie.ORCID 0000-0001-6798-2158
Aoife BranaganDiscipline of Paediatrics, Trinity College Dublin, the University of Dublin, Dublin, Ireland.
Tim HurleyDiscipline of Paediatrics, Trinity College Dublin, the University of Dublin, Dublin, Ireland.
Fiona QuirkeHealth Research Board Neonatal Encephalopathy PhD Training Network (NEPTuNE), Dublin, Ireland.
Declan DevaneHealth Research Board-Trials Methodology Research Network (HRB-TMRN), University of Galway, Galway, Ireland.
Petek E TaneriHealth Research Board-Trials Methodology Research Network (HRB-TMRN), University of Galway, Galway, Ireland.
Mohamed El-DibDepartment of Pediatric Newborn Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Frank H BloomfieldLiggins Institute, University of Auckland, Auckland, New Zealand.
Beccy MaesoJames Lind Alliance, School of Healthcare Enterprise and Innovation, University of Southampton, Southampton, UK.
Betsy PilonHope for HIE, West Bloomfield, MI, USA.
Sonia L BonifacioDivision of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University School of Medicine, Palo Alto, CA, USA.
Courtney J WusthoffDivision of Child Neurology, Stanford University, Palo Alto, CA, USA.
Lina ChalakDivision of Neonatal-Perinatal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Cynthia BearerDivision of Neonatology, Department of Pediatrics, Rainbow Babies & Children's Hospital, Cleveland, OH, USA.
Deirdre M MurrayINFANT Research Centre, Cork, Ireland.
Nadia BadawiCerebral Palsy Alliance Research Institute, Specialty of Child & Adolescent Health, Sydney Medical School, Faculty of Medicine & Health, The University of Sydney, Sydney, NSW, Australia.
Suzann CampbellDepartment of Physical Therapy, College of Applied Health Sciences, University of Illinois at Chicago, Chicago, IL, USA.
Sarah MulkeyPrenatal Pediatrics Institute, Children's National Hospital, Washington, DC, USA.
Pierre GressensUniversité Paris Cité, NeuroDiderot, Inserm, F-75019, Paris, France.
Donna M FerrieroDepartment of Pediatrics and Neurology, University of California San Francisco, Weill Institute for Neurosciences, San Francisco, CA, 94158, USA.
Linda S de VriesDepartment of Neonatology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, the Netherlands.
Karen WalkerDepartment of Newborn Care, Royal Prince Alfred Hospital, Sydney Local Health District, Sydney, NSW, Australia.
Sarah KayPEEPS-HIE, Manchester, UK.
Geraldine BoylanINFANT Research Centre, Cork, Ireland.
Chris GaleNeonatal Medicine, School of Public Health, Faculty of Medicine, Chelsea and Westminster Campus, Imperial College London, London, UK.
Nicola J RobertsonInstitute for Women's Health, University College London, London, UK.
Mary D'AltonDepartment of Obstetrics and Gynecology, Columbia University, New York, NY, USA.
Alistair GunnDepartments of Physiology and Paediatrics, School of Medical Sciences, University of Auckland, Auckland, New Zealand.
Karin B NelsonNational Institutes of Health, National Institute of Neurological Diseases and Stroke, Bethesda, MD, USA.
Steering Group for DEFiNE (Definition of Neonatal Encephalopathy)
Funding
Project IV- Cerebellar Function After Hypoxia-Ischemia and Precipitating InflammationP01HD085928 · NICHD · UNIVERSITY OF MARYLAND BALTIMORE · PI BEARER, CYNTHIA FRANCES, MCCARTHY, MARGARET M. · 2016 to 2020
$6.3M"1/6" Planning for the HEALthy Early Development StudyR34DA050342 · NIDA · CASE WESTERN RESERVE UNIVERSITY · PI SINGER, LYNN T · 2019 to 2020
$703kMedical Research Council MR/V036866/1NICHD NIH HHS P01 HD085928NIDA NIH HHS R34 DA050342
Abstract
PubMed holds no abstract for this paper.
Indexed as
Hypoxia-Ischemia, BrainInfant, Newborn, DiseasesConsensusHumansInfant, Newborn
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.