Evidence map›Paper›PMID 37572325›Full record

ArticleSTAR protocols2023

Protocol for geometric transformation of cognitive maps for generalization across hippocampal-prefrontal circuits.

Justin D Shin, Wenbo Tang, Shantanu P Jadhav

Abstract read
In one paragraph

Article in STAR protocols, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Justin D ShinNeuroscience Program, Department of Psychology, Volen National Center for Complex Systems, Brandeis University, Waltham, MA 02453, USA. Electronic address: jdshin@brandeis.edu.
Wenbo TangNeuroscience Program, Department of Psychology, Volen National Center for Complex Systems, Brandeis University, Waltham, MA 02453, USA.
Shantanu P JadhavNeuroscience Program, Department of Psychology, Volen National Center for Complex Systems, Brandeis University, Waltham, MA 02453, USA. Electronic address: shantanu@brandeis.edu.

Funding

Quantitative Neuroscience: Tools for Bridging Levels of AnalysisT32NS007292 · NINDS · BRANDEIS UNIVERSITY · PI GINA G TURRIGIANO · 1986 to 2026
$12.7M
Role of physiological patterns in hippocampal-prefrontal interactionsR01MH112661 · NIMH · BRANDEIS UNIVERSITY · PI Shantanu P Jadhav · 2017 to 2026
$3.6M
NIMH NIH HHS R01 MH112661NINDS NIH HHS T32 NS007292
6 · The paper itself

Abstract

Memory generalization is the ability to abstract knowledge from prior experiences and is critical for flexible behavior in novel situations. Here, we describe a protocol for simultaneous recording of hippocampal (area CA1)-prefrontal cortical neural ensembles in Long-Evans rats during task generalization across two distinct environments. We describe steps for building and assembling experimental apparatuses, animal preparation and surgery, and performing experiments. We then detail procedures for histology, data processing, and assessing population geometry using Uniform Manifold Approximation and Projection. For complete details on the use and execution of this protocol, please refer to Tang et al. (2023).

Indexed as

Generalization, PsychologicalHippocampusAnimalsCognitionRatsRats, Long-EvansBehaviorCognitive NeuroscienceNeuroscience

Identifiers

PMID37572325
PMCPMC10448425

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.