Evidence map›Paper›PMID 37572216›Full record

ArticlePharmacological reports : PR2023

Novel object recognition test as an alternative approach to assessing the pharmacological profile of sigma-1 receptor ligands.

Katarzyna Szczepańska, Andrzej J Bojarski, Piotr Popik, Natalia Malikowska-Racia

Open access · hybridAbstract read
In one paragraph

Article in Pharmacological reports : PR, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Katarzyna SzczepańskaDepartment of Medicinal Chemistry, Polish Academy of Sciences, Maj Institute of Pharmacology, Smętna 12, 31-343, Kraków, Poland. k.szczep@if-pan.krakow.pl.ORCID http://orcid.org/0000-0002-6110-9400
Andrzej J BojarskiDepartment of Medicinal Chemistry, Polish Academy of Sciences, Maj Institute of Pharmacology, Smętna 12, 31-343, Kraków, Poland.ORCID http://orcid.org/0000-0003-1417-6333
Piotr PopikDepartment of Behavioral Neuroscience and Drug Development, Polish Academy of Sciences, Maj Institute of Pharmacology, Smętna 12, 31-343, Kraków, Poland.ORCID http://orcid.org/0000-0003-0722-1263
Natalia Malikowska-RaciaDepartment of Behavioral Neuroscience and Drug Development, Polish Academy of Sciences, Maj Institute of Pharmacology, Smętna 12, 31-343, Kraków, Poland.ORCID http://orcid.org/0000-0003-1250-7768
Maj Institute of Pharmacology · PLJagiellonian University · PL

Funding

Narodowe Centrum Nauki 2020/36/C/NZ7/00284
6 · The paper itself

Abstract

backgroundAlthough the terms "agonist" and "antagonist" have been used to classify sigma-1 receptor (σ

methodsIn the present study, we evaluated the pharmacological profile of selected σ

resultsBoth tested σ

conclusionsThe nonlinear dose-response effect of PRE-084 in this assay does not justify its use for routine assessment of the functional activity of σ

Indexed as

Analgesics, OpioidReceptors, sigmaAcetylcholinesteraseDonepezilLigandsOpen Field TestSigma-1 ReceptorAcetylcholinesteraseAnalgesics, OpioidDonepezilLigandsReceptors, sigmaSigma-1 ReceptorCognitionFunctional profileMemory impairmentNovel object recognition testSigma-1 receptors

Identifiers

PMID37572216
PMCPMC10539447
OpenAlexW4385783263

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.