ArticleJournal of gastroenterology2023
Brain activity in response to food images in patients with irritable bowel syndrome and functional dyspepsia.
Article in Journal of gastroenterology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 7 citations in OpenAlex.
- Development and Validation of the Food Expectation Questionnaire (FEX-Q): An Image-Based Instrument to Assess Food-Related Perceptions and Symptom Expectations.Neurogastroenterology and motility · 2026Article
- Exploring brain activity differences in functional constipation using fNIRS: a case-control study.Journal of neuroengineering and rehabilitation · 2026Article
- Imaging findings of irritable bowel syndrome patients, and the diagnostic value of irritable bowel syndrome: A systematic review.World journal of methodology · 2025Article
- Brain activity during a public-speaking situation in virtual reality in patients with irritable bowel syndrome and functional dyspepsia.Journal of gastroenterology · 2025Article
- Pattern Identification in Patients with Functional Dyspepsia Using Brain-Body Bio-Signals: Protocol of a Clinical Trial for AI Algorithm Development.Journal of clinical medicine · 2025Article
- Different Food Preferences in Patients with Gastrointestinal Disorders.Internal medicine (Tokyo, Japan) · 2024Article
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Authors and funding
18 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFunctional dyspepsia (FD) and irritable bowel syndrome (IBS) are caused and exacerbated by consumption of fatty foods. However, no study has evaluated brain activity in response to food images in patients with disorders of gut-brain interaction (DGBI). This study aimed to compare food preference and brain activity when viewing food images between patients with DGBI and healthy controls.
methodsFD and IBS were diagnosed using the ROME IV criteria. Food preference was assessed using a visual analog scale (VAS). Brain activity in the prefrontal cortex (PFC) in response to food images was investigated using functional near-infrared spectroscopy (fNIRS).
resultsForty-one patients were enrolled, including 25 with DGBI. The mean VAS scores for all foods (controls vs. FD vs. IBS: 69.1 ± 3.3 vs. 54.8 ± 3.8 vs. 62.8 ± 3.7, p = 0.02), including fatty foods (78.1 ± 5.4 vs. 43.4 ± 6.3 vs. 64.7 ± 6.1, p < 0.01), were the lowest in patients with FD among all groups. Patients with FD had significantly higher brain activity in the left PFC than those with IBS and healthy controls (mean z-scores in controls vs. FD vs. IBS: - 0.077 ± 0.03 vs. 0.125 ± 0.04 vs. - 0.002 ± 0.03, p < 0.001).
conclusionsPatients with DGBI, particularly those with FD, disliked fatty foods. The brain activity in patients with DGBI differed from that in healthy controls. Increased activity in the PFC of patients with FD was confirmed.
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