Evidence map›Paper›PMID 37572046›Full record

ArticleEuropace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology2023

Cardiac implantable electronic device implantation and device-related infection.

Vivek Modi, Kashyap Shah, Bruce Ferraro, Leyla Gasimli-Gamache, Sudip Nanda, Steven Stevens, Jamshid Shirani

Open access · hybridAbstract read
In one paragraph

Article in Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Cost-effectiveness of an intraoperative antibacterial envelope in preventing cardiac implantable device-associated infections: a systematic review.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Pooled it
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  12. Benefits of Implantable Cardioverter-Defibrillator for Secondary Prevention in Patients With Organic Heart Disease.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2026
    Article
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  15. Materials Advances in Devices for Heart Disease Interventions.Advanced materials (Deerfield Beach, Fla.) · 2025
    Review
  16. Clinical profile and outcomes among patients with cardiac implantable electronic device presenting as isolated pocket infection, pocket-related infective endocarditis, or lead-related infective endocarditis.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Vivek ModiDepartment of Cardiology, St. Luke's University Health Network, Heart and Vascular Center, 801 Ostrum Street, Bethlehem, PA 18015, USA.ORCID 0000-0002-1245-9420
Kashyap ShahDepartment of Cardiology, St. Luke's University Health Network, Heart and Vascular Center, 801 Ostrum Street, Bethlehem, PA 18015, USA.ORCID 0000-0001-7884-1692
Bruce FerraroDepartment of Cardiology, St. Luke's University Health Network, Heart and Vascular Center, 801 Ostrum Street, Bethlehem, PA 18015, USA.ORCID 0000-0002-8361-0036
Leyla Gasimli-GamacheDepartment of Cardiology, St. Luke's University Health Network, Heart and Vascular Center, 801 Ostrum Street, Bethlehem, PA 18015, USA.
Sudip NandaDepartment of Cardiology, St. Luke's University Health Network, Heart and Vascular Center, 801 Ostrum Street, Bethlehem, PA 18015, USA.ORCID 0000-0003-3242-0539
Steven StevensDepartment of Cardiology, St. Luke's University Health Network, Heart and Vascular Center, 801 Ostrum Street, Bethlehem, PA 18015, USA.ORCID 0000-0002-2955-7959
Jamshid ShiraniDepartment of Cardiology, St. Luke's University Health Network, Heart and Vascular Center, 801 Ostrum Street, Bethlehem, PA 18015, USA.ORCID 0000-0003-0447-2542
St. Luke's University Health Network · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsCardiac implantable electronic devices (CIED) are important tools for managing arrhythmias, improving hemodynamics, and preventing sudden cardiac death. Device-related infections (DRI) remain a significant complication of CIED and are associated with major adverse outcomes. We aimed to assess the trend in CIED implantations, and the burden and morbidity associated with DRI. METHODS AND

resultsThe 2011-2018 National Inpatient Sample database was searched for admissions for CIED implantation and DRI. A total of 1 604 173 admissions for CIED implantations and 71 007 (4.4%) admissions for DRI were reported. There was no significant change in annual admission rates for DRI (3.96-4.59%, P value for trend = 0.98). Those with DRI were more likely to be male (69.3 vs. 57%, P < 0.001) and have a Charlson comorbidity index score ≥3 (46.6 vs. 36.8%, P < 0.001). The prevalence of congestive heart failure (CHF) increased in those admitted with DRI over the observation period. Pulmonary embolism, deep vein thrombosis, and post-procedural hematoma were the most common complications in those with DRI (4.1, 3.6, and 2.90%, respectively). Annual in-hospital mortality for those with DRI ranged from 3.9 to 5.8% (mean 4.4%, P value for trend = 0.07). Multivariate analysis identified CHF [odds ratio (OR) = 1.67; 95% confidence interval (CI) = 1.35-2.07], end-stage renal disease (OR = 1.90; 95% CI = 1.46-2.48), coagulopathy (OR = 2.94; 95% CI = 2.40-3.61), and malnutrition (OR = 2.50; 95% CI = 1.99-3.15) as the predictors of in-hospital mortality for patients admitted with DRI.

conclusionDevice-related infection is relatively common and continues to be associated with high morbidity and mortality. The prevalence of DRI has not changed significantly despite technical and technological advances in cardiac devices and their implantation.

Indexed as

Defibrillators, ImplantableHeart FailurePacemaker, ArtificialProsthesis-Related InfectionsArrhythmias, CardiacFemaleHospitalizationHumansMaleRetrospective StudiesRisk FactorsCardiac implantable electronic deviceCostDevice-related infectionLength of stayMortalityPrognosis

Identifiers

PMID37572046
PMCPMC10422690
OpenAlexW4385783389

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.