Evidence map›Paper›PMID 37572034›Full record

ArticleThe Journal of international medical research2023

Impact of semen oxidative stress on sperm quality: initial results from Vietnam.

Nguyen Dac Nguyen, Minh Tam Le, Hong Nhan Thi Dang, Trung Van Nguyen, Quoc Huy Vu Nguyen, Thanh Ngoc Cao

Abstract read
In one paragraph

Article in The Journal of international medical research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nguyen Dac NguyenCenter for Reproductive Endocrinology and Infertility, Hue University of Medicine and Pharmacy, Hue University, Vietnam.
Minh Tam LeCenter for Reproductive Endocrinology and Infertility, Hue University of Medicine and Pharmacy, Hue University, Vietnam.ORCID 0000-0001-6225-3108
Hong Nhan Thi DangCenter for Reproductive Endocrinology and Infertility, Hue University of Medicine and Pharmacy, Hue University, Vietnam.
Trung Van NguyenCenter for Reproductive Endocrinology and Infertility, Hue University of Medicine and Pharmacy, Hue University, Vietnam.
Quoc Huy Vu NguyenDepartment of Obstetrics and Gynecology, Hue University of Medicine and Pharmacy, Hue University, Vietnam.
Thanh Ngoc CaoCenter for Reproductive Endocrinology and Infertility, Hue University of Medicine and Pharmacy, Hue University, Vietnam.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aimed to determine the relationship between oxidative stress (OS) measured by the oxidation-reduction potential (ORP) and the results of semen analysis among men from infertile couples.

methodsThis cross-sectional study included 166 men from infertile couples, determined according to the World Health Organization guidelines. The general characteristics, semen analysis, sperm chromatin dispersion assay, and ORP of all subjects were evaluated and analyzed statistically.

resultsAmong 166 men from infertile couples, individuals with OS had a significantly higher DNA fragmentation index (DFI) than men without OS (22.37% ± 11.67% vs. 17.98% ± 8.98%). The sperm concentration, total sperm count, motility rate, and normal morphology were negatively correlated, while and an abnormal head and neck-tail were positively correlated with ORP. There was also a positive association between the DFI and OS level. The optimal ORP threshold for determining sperm quality was 0.77 mV/10

conclusionsDetermining the ORP suggests that OS has an adverse effect on the total sperm count, sperm motility, sperm concentration, morphology, vitality, and DNA fragmentation index.

Indexed as

Infertility, MaleSemenCross-Sectional StudiesDNA FragmentationHumansMaleOxidative StressSemen AnalysisSpermatozoaSperm CountSperm MotilityVietnaminfertilityoxidation–reduction potentialOxidative stressreactive oxygen speciessemen analysissperm DNA fragmentation

Identifiers

PMID37572034
PMCPMC10423449

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.