Evidence map›Paper›PMID 37571329›Full record

ArticleNutrients2023

Vitamin D Deficiency in COVID-19 Patients and Role of Calcifediol Supplementation.

Christian Mingiano, Tommaso Picchioni, Guido Cavati, Filippo Pirrotta, Marco Calabrese, Ranuccio Nuti, Stefano Gonnelli, Alberto Fortini, Bruno Frediani, Luigi Gennari and 1 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 3 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 3 syntheses or guidelines pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Observational
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Christian MingianoDepartment of Medicine Surgery and Neuroscience, University of Siena, 53100 Siena, Italy.
Tommaso PicchioniInternal Medicine Unit, Ospedale San Giovanni di Dio, 50143 Florence, Italy.
Guido CavatiDepartment of Medicine Surgery and Neuroscience, University of Siena, 53100 Siena, Italy.
Filippo PirrottaDepartment of Medicine Surgery and Neuroscience, University of Siena, 53100 Siena, Italy.
Marco CalabreseDepartment of Medicine Surgery and Neuroscience, University of Siena, 53100 Siena, Italy.
Ranuccio NutiDepartment of Medicine Surgery and Neuroscience, University of Siena, 53100 Siena, Italy.
Stefano GonnelliDepartment of Medicine Surgery and Neuroscience, University of Siena, 53100 Siena, Italy.
Alberto FortiniInternal Medicine Unit, Ospedale San Giovanni di Dio, 50143 Florence, Italy.
Bruno FredianiDepartment of Medicine Surgery and Neuroscience, University of Siena, 53100 Siena, Italy.
Luigi GennariDepartment of Medicine Surgery and Neuroscience, University of Siena, 53100 Siena, Italy.
Daniela MerlottiDepartment of Medical Sciences, Azienda Ospedaliera Universitaria Senese, 53100 Siena, Italy.ORCID 0000-0002-3338-6339
University of Siena · ITNuovo Ospedale San Giovanni di Dio · ITAzienda Ospedaliera Universitaria Senese · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypovitaminosis D has been associated with worse outcome in respiratory tract infections, with conflicting opinions regarding its role in Coronavirus-19 disease (COVID-19). Our study aimed to evaluate the possible relationship between 25-OH vitamin D (25OHD) values and the following conditions in patients hospitalized for COVID-19: prognosis, mortality, invasive (IV) and non-invasive (NIV) mechanical ventilation, and orotracheal intubation (OTI). A further objective was the analysis of a possible positive effect of supplementation with calcifediol on COVID-19 severity and prognosis. We analyzed 288 patients hospitalized at the San Giovanni di Dio Hospital in Florence and the Santa Maria alle Scotte Hospital in Siena, from November 2020 to February 2021. The 25OHD levels correlated positively with the partial pressure of oxygen and FiO2 (PaO2/FiO2) ratio (r = 0.17;

Indexed as

COVID-19Vitamin D DeficiencyCalcifediolDietary SupplementsHumansVitamin DVitaminsCalcifediolVitamin DVitamins25-OH vitamin DcalcifediolCOVID-19SARS-CoV-2vitamin D deficiencyvitamin D supplementation

Identifiers

PMID37571329
PMCPMC10421093
OpenAlexW4385422820

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.