Evidence map›Paper›PMID 37571227›Full record

ArticleNutrients2023

Mediation of BMI on 25-Hydroxyvitamin D Levels in U.S. Adults with Sugar-Sweetened Beverages Consumption.

Wei-Ting Lin, Gabrielle V Gonzalez, Yu-Hsiang Kao, Hui-Yi Lin, Mirandy S Li, David W Seal, Chien-Hung Lee, Chih-Yang Hu, Lei-Shih Chen, Tung-Sung Tseng

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Wei-Ting LinSocial, Behavioral, and Population Sciences, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112, USA.ORCID 0000-0001-5556-2754
Gabrielle V GonzalezBehavioral and Community Health Sciences Program, School of Public Health, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.
Yu-Hsiang KaoBehavioral and Community Health Sciences Program, School of Public Health, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.
Hui-Yi LinBiostatistics Program, School of Public Health, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.ORCID 0000-0002-3307-5549
Mirandy S LiBehavioral and Community Health Sciences Program, School of Public Health, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.
David W SealSocial, Behavioral, and Population Sciences, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112, USA.ORCID 0000-0002-5802-7148
Chien-Hung LeeDepartment of Public Health, College of Health Science, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.ORCID 0000-0002-0988-264X
Chih-Yang HuEnvironmental and Occupational Health Sciences, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.
Lei-Shih ChenDepartment of Health and Kinesiology, Texas A&M University, College Station, TX 77843, USA.ORCID 0000-0001-5320-6350
Tung-Sung TsengBehavioral and Community Health Sciences Program, School of Public Health, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.ORCID 0000-0001-6266-9891
Louisiana State University Health Sciences Center New Orleans · USTulane University · USKaohsiung Medical University · TWTexas A&M University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Body mass index (BMI) as well as sugar-sweetened beverages (SSB) has been suggested to independently decrease 25-hydroxyvitamin D (25(OH)D). However, the relationship between SSB, BMI, and 25(OH)D is uncertain. This study aimed to investigate the potential mediating role of BMI in the association between SSB intake and 25(OH)D. A total of 4505 representative U.S. adults aged above 20 years and without liver conditions were selected from the 2013-2014 NHANES. All analyses were performed under survey modules with appropriate sampling weights. The prevalence of 25(OH)D insufficiency and deficiency was 37.8% and 24.1% in U.S. adults, respectively. Compared with non-SSB consumers, an increased risk of vitamin D deficiency was found in either heavy SSB consumers or soda consumers, respectively (aOR = 2.10, 95% CI = 1.25-3.54 in heavy SSB consumers; aOR = 1.61, 95% CI = 1.06-2.44 in soda consumers). Around 21.3% of the total effect of sugar intake from SSB on decreased 25(OH)D was explained by BMI. In conclusion, high total sugar intake from SSB and BMI independently contribute to lower 25(OH)D, and BMI mediates the inverse association between total sugar intake from SSB intake and 25(OH)D. Furthermore, an increased risk of having vitamin D deficiency was found in the population who consumed higher levels of sugar from SSB or soda drinks.

Indexed as

Sugar-Sweetened BeveragesVitamin D DeficiencyAdultBeveragesBody Mass IndexCalcifediolHumansNutrition SurveysSugarsVitamin D25-hydroxyvitamin DCalcifediolSugarsVitamin D25-hydroxyvitamin D (25(OH)D)body mass index (BMI)NHANESsugar-sweetened beverage (SSB)vitamin D deficiency

Identifiers

PMID37571227
PMCPMC10421177
OpenAlexW4385274369

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.