Evidence map›Paper›PMID 37571117›Full record

ArticlePolymers2023

An Innovative Biofunctional Composite Hydrogel with Enhanced Printability, Rheological Properties, and Structural Integrity for Cell Scaffold Applications.

Taufik Abdullah Mappa, Chung-Ming Liu, Chung-Chih Tseng, Muhammad Ruslin, Jui-Hung Cheng, Wen-Chien Lan, Bai-Hung Huang, Yung-Chieh Cho, Chia-Chien Hsieh, Hsin-Hui Kuo and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Polymers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Taufik Abdullah MappaSchool of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110, Taiwan.ORCID 0000-0002-1920-7621
Chung-Ming LiuDepartment of Biomedical Engineering, College of Biomedical Engineering, China Medical University, Taichung 404, Taiwan.
Chung-Chih TsengInstitute of Medical Science and Technology, National Sun Yat-sen University, Kaohsiung 804, Taiwan.ORCID 0000-0002-5791-5928
Muhammad RuslinDepartment of Oral and Maxillofacial Surgery, Faculty of Dentistry, Hasanuddin University, Makassar 90245, Indonesia.ORCID 0000-0003-0943-4000
Jui-Hung ChengDepartment of Mold and Die Engineering, National Kaohsiung University of Science and Technology, Kaohsiung 807, Taiwan.ORCID 0000-0003-2865-2943
Wen-Chien LanDepartment of Oral Hygiene Care, Ching Kuo Institute of Management and Health, Keelung 203, Taiwan.ORCID 0000-0002-2727-1172
Bai-Hung HuangGraduate Institute of Dental Science, College of Dentistry, China Medical University, Taichung 404, Taiwan.
Yung-Chieh ChoSchool of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110, Taiwan.
Chia-Chien HsiehSchool of Dental Technology, College of Oral Medicine, Taipei Medical University, Taipei 110, Taiwan.
Hsin-Hui KuoResearch Center for Biomedical Devices and Prototyping Production, Taipei Medical University, Taipei 110, Taiwan.
Chen-Han TsouDepartment of Dentistry, Zuoying Branch of Kaohsiung Armed Forces General Hospital, Kaohsiung 813, Taiwan.
Yung-Kang ShenSchool of Dental Technology, College of Oral Medicine, Taipei Medical University, Taipei 110, Taiwan.ORCID 0000-0003-4209-3551

Funding

Zuoying Armed Forces General Hospital KAFGH-ZY-A-110017
6 · The paper itself

Abstract

The present study was conducted to manipulate various biomaterials to find potential hydrogel formulations through three-dimensional (3D) bioprinting fabrication for tissue repair, reconstruction, or regeneration. The hydrogels were prepared using sodium alginate and gelatin combined with different concentrations of Pluronic F127 (6% (3 g), 8% (4 g), and 10% (5 g)) and were marked as AGF-6%, AGF-8%, and AGF-10%, respectively. The properties of the hydrogels were investigated using a contact angle goniometer, rheometer, and 3D bioprinter. In addition, the osteoblast-like cell line (MG-63) was used to evaluate the cell viability including hydrogels before and after 3D bioprinting. It was found that the ratio of contact angle was lowest at AGF-6%, and the rheological results were higher for all samples of AGF-6%, AGF-8%, and AGF-10% compared with the control sample. The printability indicated that the AGF-6% hydrogel possessed great potential in creating a cell scaffold with shape integrity. Moreover, the live/dead assay also presented the highest numbers of live cells before printing compared with after printing. However, the number of live cells on day 7 was higher than on day 1 before and after printing (**

Indexed as

biopolymercell scaffoldhydrogelsprintabilitytissue regeneration

Identifiers

PMID37571117
PMCPMC10421221

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.