Evidence map›Paper›PMID 37570790›Full record

ArticleMolecules (Basel, Switzerland)2023

Phosphodiesterase 5 and Arginase Inhibitory Activities of the Extracts from Some Members of Nelumbonaceae and Nymphaeaceae Families.

Teerapap Panklai, Nungruthai Suphrom, Prapapan Temkitthawon, Perle Totoson, Krongkarn Chootip, Xiao-Liang Yang, Hui-Ming Ge, Zhu-Jun Yao, Nattiya Chaichamnong, Kornkanok Ingkaninan and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Avicenna journal of phytomedicine
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 3 countries.

Teerapap PanklaiCenter of Excellence in Cannabis Research, Faculty of Pharmaceutical Sciences and Center of Excellence for Innovation in Chemistry, Naresuan University, Phitsanulok 65000, Thailand.
Nungruthai SuphromDepartment of Chemistry, Faculty of Science and Center of Excellence for Innovation in Chemistry, Naresuan University, Phitsanulok 65000, Thailand.ORCID 0000-0003-3767-8387
Prapapan TemkitthawonCenter of Excellence in Cannabis Research, Faculty of Pharmaceutical Sciences and Center of Excellence for Innovation in Chemistry, Naresuan University, Phitsanulok 65000, Thailand.
Perle TotosonUniversité de Franche-Comté, PEPITE, 25000 Besançon, France.
Krongkarn ChootipDepartment of Physiology, Faculty of Medical Science and Center of Excellence for Innovation in Chemistry, Naresuan University, Phitsanulok 65000, Thailand.ORCID 0000-0001-6973-158X
Xiao-Liang YangState Key Laboratory of Coordination Chemistry, Jiangsu Key Laboratory of Advance Organic Materials, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China.
Hui-Ming GeState Key Laboratory of Pharmaceutical Biotechnology, Institute of Functional Biomolecules, School of Life Sciences, Nanjing University, Nanjing 210023, China.
Zhu-Jun YaoState Key Laboratory of Coordination Chemistry, Jiangsu Key Laboratory of Advance Organic Materials, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China.
Nattiya ChaichamnongDivision of Applied Thai Traditional Medicine, Faculty of Public Health, Naresuan University, Phitsanulok 65000, Thailand.
Kornkanok IngkaninanCenter of Excellence in Cannabis Research, Faculty of Pharmaceutical Sciences and Center of Excellence for Innovation in Chemistry, Naresuan University, Phitsanulok 65000, Thailand.ORCID 0000-0002-4415-8489
Corine GirardUniversité de Franche-Comté, PEPITE, 25000 Besançon, France.ORCID 0000-0002-5116-1395
Naresuan University · THNanjing University · CNUniversité de franche-comté · FR

Funding

The Agricultural Research Development Agency (Public Organization) CRP6305030410The National Science, Research and Innovation Fund (NSRF) via the Program Management Unit for Human Resources & Institutional Development, Research and Innovation B16F640099
6 · The paper itself

Abstract

The objectives of this study were (1) to investigate the effect of extracts from some plants in the families Nelumbonaceae and Nymphaeaceae on phosphodiesterase 5 (PDE5) and arginase, which have been used in erectile dysfunction treatment, and (2) to isolate and identify the compounds responsible for such activities. The characterization and quantitative analysis of flavonoid constituents in the active extracts were performed by HPLC. Thirty-seven ethanolic extracts from different parts of plants in the genus

Indexed as

NelumboNelumbonaceaeNymphaeaNymphaeaceaeArginaseCyclic Nucleotide Phosphodiesterases, Type 5FlavonoidsHumansMalePlant ExtractsQuercetinArginaseCyclic Nucleotide Phosphodiesterases, Type 5FlavonoidsPlant ExtractsQuercetinarginaseerectile dysfunctionflavonoidslotusNymphaea pubescensphosphodiesterase 5water lily

Identifiers

PMID37570790
PMCPMC10420992
OpenAlexW4385497775

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.