Evidence map›Paper›PMID 37570681›Full record

ArticleMolecules (Basel, Switzerland)2023

Determination of the Bioactive Compounds from

Cristina Burlou-Nagy, Florin Bănică, Rodica Anamaria Negrean, Tünde Jurca, Laura Grațiela Vicaș, Eleonora Marian, Ildikó Bácskay, Rita Kiss, Pálma Fehér, Simona Ioana Vicaș and 3 more

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Evaluation ofMedical sciences (Basel, Switzerland) · 2026
    Article
  5. Article
  6. Activity of BiocidinFrontiers in antibiotics · 2025
    Article
  7. Review
  8. Echinacea: Bioactive Compounds and Agronomy.Plants (Basel, Switzerland) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Cristina Burlou-NagyDoctoral School of Biomedical Sciences, University of Oradea, Universitatii Street, 1, 410087 Oradea, Romania.ORCID 0000-0001-6563-5929
Florin BănicăDepartment of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, 29 Nicolae Jiga Street, 410028 Oradea, Romania.
Rodica Anamaria NegreanDepartment of Preclinical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 1st December Square 10, 410068 Oradea, Romania.
Tünde JurcaDepartment of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, 29 Nicolae Jiga Street, 410028 Oradea, Romania.ORCID 0000-0001-5591-7826
Laura Grațiela VicașDepartment of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, 29 Nicolae Jiga Street, 410028 Oradea, Romania.ORCID 0000-0001-5328-333X
Eleonora MarianDepartment of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, 29 Nicolae Jiga Street, 410028 Oradea, Romania.ORCID 0000-0002-6181-1590
Ildikó BácskayDepartment of Pharmaceutical Technology, Faculty of Pharmacy, University of Debrecen, Nagyerdei krt. 98, H-4032 Debrecen, Hungary.ORCID 0000-0001-8663-2890
Rita KissDepartment of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Debrecen, Nagyerdei krt. 98, H-4032 Debrecen, Hungary.ORCID 0000-0003-1208-366X
Pálma FehérDepartment of Pharmaceutical Technology, Faculty of Pharmacy, University of Debrecen, Nagyerdei krt. 98, H-4032 Debrecen, Hungary.
Simona Ioana VicașDepartment of Food Engineering, Faculty of Environmental Protection, University of Oradea, No. 26 General Magheru Avenue, 410087 Oradea, Romania.ORCID 0000-0001-9562-4809
Florina Miere GrozaDepartment of Preclinical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 1st December Square 10, 410068 Oradea, Romania.ORCID 0000-0002-8420-024X
Adriana Ramona MemeteDepartment of Food Engineering, Faculty of Environmental Protection, University of Oradea, No. 26 General Magheru Avenue, 410087 Oradea, Romania.ORCID 0000-0001-6045-1936
Annamaria PallagDoctoral School of Biomedical Sciences, University of Oradea, Universitatii Street, 1, 410087 Oradea, Romania.ORCID 0000-0002-7146-3040

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed at the relationship between antioxidant capacity, antimicrobial activity, and in vitro evaluation of the wound healing effect of the extract obtained from Echinaceae purpureae folium (EPF). This study's objective was to assess the bioactive components (total phenol and flavonoid content) and antioxidant activity of EPF extracts using the DPPH test method. The antioxidant capacity and the quantities of the compounds with antioxidant capacity were evaluated by spectrophotometric methods. Antimicrobial activity has been investigated against various pathogenic microorganisms. The minimum inhibitory concentration was determined by the microdilution method. Additionally, our work used a scratch test to examine the in vitro wound healing effects of EPF extract on NHDF cells. Statistical analysis was used to quantify the rate of migration and proliferation of fibroblast cells within the wound. Microscope pictures of fibroblast cells exposed to various EPF extract dosages were processed to estimate the width of the wound, area of the wound, and cell density inside the wound. The study proved that there was a relationship between the antioxidant, antimicrobial, and wound healing ability of EPF extracts.

Indexed as

Anti-Infective AgentsEchinaceaAntioxidantsPlant ExtractsPlant LeavesWound HealingAnti-Infective AgentsAntioxidantsPlant Extractsantimicrobial activityantioxidant capacityEchinacea purpurea (L.) Moenchwound healing potential

Identifiers

PMID37570681
PMCPMC10420800

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.