Evidence map›Paper›PMID 37570600›Full record

ReviewMolecules (Basel, Switzerland)2023

Interface Chirality: From Biological Effects to Biomedical Applications.

Liting Guo, Yanqiu Guo, Rui Wang, Jie Feng, Nannan Shao, Xiaolin Zhou, Yunlong Zhou

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Liting GuoJoint Research Centre on Medicine, Affiliated Xiangshan Hospital, Wenzhou Medical University, Ningbo 315700, China.
Yanqiu GuoZhejiang Engineering Research Center for Tissue Repair Materials, Wenzhou Institute, University of Chinese Academy of Sciences, Wenzhou 325000, China.
Rui WangZhejiang Engineering Research Center for Tissue Repair Materials, Wenzhou Institute, University of Chinese Academy of Sciences, Wenzhou 325000, China.
Jie FengSchool of Pharmacy, Queens University Belfast, 97 Lisburn Road, Belfast BT9 7BL, UK.
Nannan ShaoZhejiang Engineering Research Center for Tissue Repair Materials, Wenzhou Institute, University of Chinese Academy of Sciences, Wenzhou 325000, China.
Xiaolin ZhouZhejiang Engineering Research Center for Tissue Repair Materials, Wenzhou Institute, University of Chinese Academy of Sciences, Wenzhou 325000, China.
Yunlong ZhouJoint Research Centre on Medicine, Affiliated Xiangshan Hospital, Wenzhou Medical University, Ningbo 315700, China.ORCID 0000-0001-5654-1170

Funding

Diagnosis & Treatment Devices of Zhejiang Province WIBEK181006Major Science and Technology Project of Wenzhou Science and Technology ZG2022017National Natural Science Foundation of China 21773172Public Welfare Science and Technology Plan of Wenzhou Y2020237 and Y20210043Research Center of Clinical Functional Materials WIUCASQD 2019001
6 · The paper itself

Abstract

Chiral surface is a critical mediator that significantly impacts interaction with biological systems on regulating cell behavior. To better understand how the properties of interfacial Chirality affect cell behavior and address the limitations of chiral materials for biomedical applications, in this review, we mainly focus on the recent developments of chiral bio-interfaces for the controllable and accurate guidance of chiral biomedical phenomena. In particular, we will discuss how cells or organisms sense and respond to the chiral stimulus, as well as the chirality mediating cell fate, tissue repair, and organism immune response will be reviewed. In addition, the biological applications of chirality, such as drug delivery, antibacterial, antivirus and antitumor activities, and biological signal detection, will also be reviewed. Finally, the challenges of chiral bio-interfaces for controlling biological response and the further application of interface chirality materials for biomedical will be discussed.

Indexed as

StereoisomerismCell Differentiationapplicationcell fatechiralityimmunityinterfacetissue repair

Identifiers

PMID37570600
PMCPMC10419656

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.