Evidence map›Paper›PMID 37570503›Full record

ReviewNanomaterials (Basel, Switzerland)2023

Biomaterials and Encapsulation Techniques for Probiotics: Current Status and Future Prospects in Biomedical Applications.

Qiqi Sun, Sheng Yin, Yingxu He, Yi Cao, Chunping Jiang

Abstract readReview
In one paragraph

Review in Nanomaterials (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  14. In Vivo Evaluation of the Effect ofInternational journal of molecular sciences · 2026
    Article
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3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Qiqi SunJinan Microecological Biomedicine Shandong Laboratory, Shounuo City Light West Block, Jinan 250117, China.ORCID 0000-0002-4148-027X
Sheng YinJinan Microecological Biomedicine Shandong Laboratory, Shounuo City Light West Block, Jinan 250117, China.
Yingxu HeSchool of Computing, National University of Singapore, Singapore 119077, Singapore.
Yi CaoJinan Microecological Biomedicine Shandong Laboratory, Shounuo City Light West Block, Jinan 250117, China.ORCID 0000-0003-1493-7868
Chunping JiangJinan Microecological Biomedicine Shandong Laboratory, Shounuo City Light West Block, Jinan 250117, China.

Funding

Research Project of Jinan Microecological Biomedicine Shandong Laboratory JNL-2022004AResearch Project of Jinan Microecological Biomedicine Shandong Laboratory JNL-2023020D
6 · The paper itself

Abstract

Probiotics have garnered significant attention in recent years due to their potential advantages in diverse biomedical applications, such as acting as antimicrobial agents, aiding in tissue repair, and treating diseases. These live bacteria must exist in appropriate quantities and precise locations to exert beneficial effects. However, their viability and activity can be significantly impacted by the surrounding tissue, posing a challenge to maintain their stability in the target location for an extended duration. To counter this, researchers have formulated various strategies that enhance the activity and stability of probiotics by encapsulating them within biomaterials. This approach enables site-specific release, overcoming technical impediments encountered during the processing and application of probiotics. A range of materials can be utilized for encapsulating probiotics, and several methods can be employed for this encapsulation process. This article reviews the recent advancements in probiotics encapsulated within biomaterials, examining the materials, methods, and effects of encapsulation. It also provides an overview of the hurdles faced by currently available biomaterial-based probiotic capsules and suggests potential future research directions in this field. Despite the progress achieved to date, numerous challenges persist, such as the necessity for developing efficient, reproducible encapsulation methods that maintain the viability and activity of probiotics. Furthermore, there is a need to design more robust and targeted delivery vehicles.

Indexed as

biomimetic materialsmicroecologyprobioticstissue engineering

Identifiers

PMID37570503
PMCPMC10421492

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.