Evidence map›Paper›PMID 37570331›Full record

ArticleAnimals : an open access journal from MDPI2023

Use of Danish National Somatic Cell Count Data to Assess the Need for Dry-Off Treatment in Holstein Dairy Cattle.

Maj Beldring Henningsen, Matt Denwood, Carsten Thure Kirkeby, Søren Saxmose Nielsen

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Maj Beldring HenningsenAnimal Welfare and Disease Control, Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, 1870 Frederiksberg, Denmark.ORCID 0000-0002-4518-1592
Matt DenwoodAnimal Welfare and Disease Control, Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, 1870 Frederiksberg, Denmark.ORCID 0000-0001-5212-4273
Carsten Thure KirkebyAnimal Welfare and Disease Control, Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, 1870 Frederiksberg, Denmark.
Søren Saxmose NielsenAnimal Welfare and Disease Control, Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, 1870 Frederiksberg, Denmark.ORCID 0000-0003-2417-0787
University of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In Denmark, PCR testing of dairy cattle is commonly used to select animals for the antibacterial treatment of intramammary infection (IMI) during the dry-off period. IMI is associated with a high somatic cell count (SCC), routinely recorded for milk quality control for most commercial dairy herds. This study aimed to compare SCC curves over the lactation among dairy cows with positive vs. negative PCR test results for four major IMI pathogens. Data from 133,877 PCR-tested Holstein cows from 1364 Danish conventional dairy herds were used to fit a nonlinear mixed-effects model using a modified four-parameter Wilmink function. We stratified the data into first, second, third or fourth and later parity and fitted Wilmink curves to all SCC observations between 6 and 305 days in milk. The PCR tests were taken before dry-off at the end of the lactation to investigate which animals qualified for selective dry cow therapy. A PCR Ct-value of 37 and below was used to determine if an animal was PCR positive for any of the following IMI pathogens:

Indexed as

mastitisPCR testingwilmink function

Identifiers

PMID37570331
PMCPMC10416964
OpenAlexW4385576585

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.