Evidence map›Paper›PMID 37569870›Full record

ArticleInternational journal of molecular sciences2023

Physicochemical Characterization of Chitosan/Poly-γ-Glutamic Acid Glass-like Materials.

Sondos Hejazi, Odile Francesca Restaino, Mohammed Sabbah, Domenico Zannini, Rocco Di Girolamo, Angela Marotta, Sergio D'Ambrosio, Irene Russo Krauss, C Valeria L Giosafatto, Gabriella Santagata and 2 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sondos HejaziDepartment of Chemical Sciences, University of Naples "Federico II", 80126 Naples, Italy.ORCID 0000-0002-2237-9467
Odile Francesca RestainoDepartment of Chemical Sciences, University of Naples "Federico II", 80126 Naples, Italy.
Mohammed SabbahDepartment of Nutrition and Food Technology, An-Najah National University, Nablus P400, Palestine.ORCID 0000-0003-4631-8156
Domenico ZanniniDepartment of Chemical Sciences, University of Naples "Federico II", 80126 Naples, Italy.ORCID 0000-0002-2855-748X
Rocco Di GirolamoDepartment of Chemical Sciences, University of Naples "Federico II", 80126 Naples, Italy.ORCID 0000-0001-8815-2997
Angela MarottaDepartment of Chemical, Materials and Production Engineering (DICMaPI), University of Naples "Federico II", 80126 Naples, Italy.ORCID 0000-0002-5901-324X
Sergio D'AmbrosioDepartment of Experimental Medicine, Section of Biotechnology and Molecular Biology, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0001-8031-7697
Irene Russo KraussDepartment of Chemical Sciences, University of Naples "Federico II", 80126 Naples, Italy.ORCID 0000-0001-8124-6034
C Valeria L GiosafattoDepartment of Chemical Sciences, University of Naples "Federico II", 80126 Naples, Italy.ORCID 0000-0001-8762-2205
Gabriella SantagataInstitute for Polymers, Composites, and Biomaterials, National Council of Research, 80078 Pozzuoli, Italy.ORCID 0000-0002-3370-195X
Chiara SchiraldiDepartment of Experimental Medicine, Section of Biotechnology and Molecular Biology, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0002-1066-843X
Raffaele PortaDepartment of Chemical Sciences, University of Naples "Federico II", 80126 Naples, Italy.ORCID 0000-0003-4455-0664

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This paper sets up a new route for producing non-covalently crosslinked bio-composites by blending poly-γ-glutamic acid (γ-PGA) of microbial origin and chitosan (CH) through poly-electrolyte complexation under specific experimental conditions. CH and two different molecular weight γ-PGA fractions have been blended at different mass ratios (1/9, 2/8 and 3/7) under acidic pH. The developed materials seemed to behave like moldable hydrogels with a soft rubbery consistency. However, after dehydration, they became exceedingly hard, glass-like materials completely insoluble in water and organic solvents. The native biopolymers and their blends underwent comprehensive structural, physicochemical, and thermal analyses. The study confirmed strong physical interactions between polysaccharide and polyamide chains, facilitated by electrostatic attraction and hydrogen bonding. The materials exhibited both crystalline and amorphous structures and demonstrated good thermal stability and degradability. Described as thermoplastic and saloplastic, these bio-composites offer vast opportunities in the realm of polyelectrolyte complexes (PECs). This unique combination of properties allowed the bio-composites to function as glass-like materials, making them highly versatile for potential applications in various fields. They hold potential for use in regenerative medicine, biomedical devices, food packaging, and 3D printing. Their environmentally friendly properties make them attractive candidates for sustainable material development in various industries.

Indexed as

ChitosanBiocompatible MaterialsGlutamic AcidPolyelectrolytesPolyglutamic AcidRegenerative MedicineBiocompatible MaterialsChitosanGlutamic AcidPolyelectrolytesPolyglutamic Acidbioplasticschitosancrosslinked materialsglass-like materialsphysicochemical characterizationpolyelectrolytes complexationpoly-γ-glutamic acid

Identifiers

PMID37569870
PMCPMC10419765

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.