Evidence map›Paper›PMID 37569857›Full record

ArticleInternational journal of molecular sciences2023

IL-23/IL-17 Axis in Chronic Hepatitis C and Non-Alcoholic Steatohepatitis-New Insight into Immunohepatotoxicity of Different Chronic Liver Diseases.

Ankica Vujovic, Andjelka M Isakovic, Sonja Misirlic-Dencic, Jovan Juloski, Milan Mirkovic, Andja Cirkovic, Marina Djelic, Ivana Milošević

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ankica VujovicClinic for Infectious and Tropical Diseases, University Clinical Center of Serbia, 11 000 Belgrade, Serbia.ORCID 0000-0001-9570-215X
Andjelka M IsakovicInstitute of Medical and Clinical Biochemistry, Faculty of Medicine, University of Belgrade, 11 000 Belgrade, Serbia.ORCID 0000-0001-5270-709X
Sonja Misirlic-DencicInstitute of Medical and Clinical Biochemistry, Faculty of Medicine, University of Belgrade, 11 000 Belgrade, Serbia.ORCID 0000-0002-8635-4701
Jovan JuloskiFaculty of Medicine, University of Belgrade, 11 000 Belgrade, Serbia.
Milan MirkovicInstitute for Orthopedic Surgery "Banjica", 11 000 Belgrade, Serbia.
Andja CirkovicDepartment of Medical Statistics, Faculty of Medicine, University of Belgrade, 11 000 Belgrade, Serbia.
Marina DjelicInstitute of Medical Physiology, Faculty of Medicine, University of Belgrade, 11 000 Belgrade, Serbia.
Ivana MiloševićClinic for Infectious and Tropical Diseases, University Clinical Center of Serbia, 11 000 Belgrade, Serbia.
University of Belgrade · RSInstitute of Orthopedics Banjica · RS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Considering the relevance of the research of pathogenesis of different liver diseases, we investigated the possible activity of the IL-23/IL-17 axis on the immunohepatotoxicity of two etiologically different chronic liver diseases. A total of 36 chronic hepatitis C (CHC) patients, 16 with (CHC-SF) and 20 without significant fibrosis (CHC-NSF), 19 patients with non-alcoholic steatohepatitis (NASH), and 20 healthy controls (CG) were recruited. Anthropometric, biochemical, and immunological cytokines (IL-6, IL-10, IL-17 and IL-23) tests were performed in accordance with standard procedure. Our analysis revealed that a higher concentration of plasma IL-23 was associated with NASH (

Indexed as

Hepatitis C, ChronicInterleukin-17Interleukin-23Non-alcoholic Fatty Liver DiseaseAdultBiomarkersCase-Control StudiesFemaleHumansInterleukin-10Liver CirrhosisMaleMiddle AgedBiomarkersIL17A protein, humanInterleukin-10Interleukin-17Interleukin-23chronic hepatitis CIL-23/IL-17 axisimmunohepatotoxicitynon-alcoholic steatohepatitis

Identifiers

PMID37569857
PMCPMC10419971
OpenAlexW4385607494

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.