Evidence map›Paper›PMID 37569802›Full record

ArticleInternational journal of molecular sciences2023

A Potential Association between Ribonuclease 1 Dynamics in the Blood and the Outcome in COVID-19 Patients.

Elisabeth Zechendorf, Christian Beckers, Nadine Frank, Sandra Kraemer, Carolina Neu, Thomas Breuer, Michael Dreher, Edgar Dahl, Gernot Marx, Lukas Martin and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Elisabeth ZechendorfDepartment of Intensive Care and Intermediate Care, University Hospital RWTH Aachen, 52074 Aachen, Germany.
Christian BeckersDepartment of Intensive Care and Intermediate Care, University Hospital RWTH Aachen, 52074 Aachen, Germany.
Nadine FrankDepartment of Intensive Care and Intermediate Care, University Hospital RWTH Aachen, 52074 Aachen, Germany.
Sandra KraemerDepartment of Intensive Care and Intermediate Care, University Hospital RWTH Aachen, 52074 Aachen, Germany.ORCID 0000-0002-2958-843X
Carolina NeuDepartment of Intensive Care and Intermediate Care, University Hospital RWTH Aachen, 52074 Aachen, Germany.ORCID 0009-0005-1431-8743
Thomas BreuerDepartment of Intensive Care and Intermediate Care, University Hospital RWTH Aachen, 52074 Aachen, Germany.ORCID 0000-0003-3804-8811
Michael DreherDepartment of Pneumology and Intensive Care Medicine, University Hospital RWTH Aachen, 52074 Aachen, Germany.ORCID 0000-0002-3452-5329
Edgar DahlRWTH Centralized Biomaterial Bank (RWTH cBMB) at the Institute of Pathology, University Hospital RWTH Aachen, 52074 Aachen, Germany.ORCID 0000-0002-8439-7994
Gernot MarxDepartment of Intensive Care and Intermediate Care, University Hospital RWTH Aachen, 52074 Aachen, Germany.
Lukas MartinDepartment of Intensive Care and Intermediate Care, University Hospital RWTH Aachen, 52074 Aachen, Germany.
Tim-Philipp SimonDepartment of Intensive Care and Intermediate Care, University Hospital RWTH Aachen, 52074 Aachen, Germany.
RWTH Aachen University · DE

Funding

RWTH Aachen University START 131/19
6 · The paper itself

Abstract

The COVID-19 pandemic caused by the new SARS-CoV-2 coronavirus is the most recent and well-known outbreak of a coronavirus. RNase 1 is a small endogenous antimicrobial polypeptide that possesses antiviral activity against viral diseases. In this study, we investigated a potential association between ribonuclease 1 and the outcome in COVID-19 patients and the impact of increased and decreased RNase 1 levels serum during the course of the disease. Therefore, two patient populations, Cohort A (

Indexed as

AdultAgedBiomarkersCOVID-19CreatinineFemaleHumansMaleMiddle AgedPandemicsPrognosisSARS-CoV-2BiomarkersCreatininebiomarkerCOVID-19kidney injuryRNase 1SARS-CoV-2

Identifiers

PMID37569802
PMCPMC10419077
OpenAlexW4385578026

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.