Evidence map›Paper›PMID 37569675›Full record

ArticleInternational journal of molecular sciences2023

Effects of Zinc Oxide Nanoparticle Exposure on Human Glial Cells and Zebrafish Embryos.

Vanessa Valdiglesias, Anabel Alba-González, Natalia Fernández-Bertólez, Assia Touzani, Lucía Ramos-Pan, Ana Teresa Reis, Jorge Moreda-Piñeiro, Julián Yáñez, Blanca Laffon, Mónica Folgueira

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Cardiovascular Toxicity of Metal-Based Nanoparticles.International journal of molecular sciences · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Vanessa ValdiglesiasUniversidade da Coruña, Grupo NanoToxGen, Centro Interdisciplinar de Química e Bioloxía-CICA, Departamento de Biología, Facultad de Ciencias, Campus A Zapateira s/n, 15071 A Coruña, Spain.ORCID 0000-0002-5572-1089
Anabel Alba-GonzálezUniversidade da Coruña, Grupo NEUROVER, Centro Interdisciplinar de Química e Bioloxía-CICA, Rúa As Carballeiras, 15071 A Coruña, Spain.ORCID 0000-0003-1627-3006
Natalia Fernández-BertólezUniversidade da Coruña, Grupo NanoToxGen, Centro Interdisciplinar de Química e Bioloxía-CICA, Departamento de Biología, Facultad de Ciencias, Campus A Zapateira s/n, 15071 A Coruña, Spain.ORCID 0000-0001-7537-3977
Assia TouzaniUniversidade da Coruña, Grupo NanoToxGen, Centro Interdisciplinar de Química e Bioloxía-CICA, Departamento de Biología, Facultad de Ciencias, Campus A Zapateira s/n, 15071 A Coruña, Spain.
Lucía Ramos-PanUniversidade da Coruña, Grupo NanoToxGen, Centro Interdisciplinar de Química e Bioloxía-CICA, Departamento de Biología, Facultad de Ciencias, Campus A Zapateira s/n, 15071 A Coruña, Spain.
Ana Teresa ReisEPIUnit-Instituto de Saúde Pública, Universidade do Porto, Rua das Taipas 135, 4050-600 Porto, Portugal.ORCID 0000-0001-7150-997X
Jorge Moreda-PiñeiroUniversidade da Coruña, Grupo Química Analítica Aplicada (QANAP), Instituto Universitario Medio Ambiente (IUMA), Departamento de Química, Facultad de Ciencias, Campus A Zapateira s/n, 15071 A Coruña, Spain.ORCID 0000-0001-6101-1879
Julián YáñezUniversidade da Coruña, Grupo NEUROVER, Centro Interdisciplinar de Química e Bioloxía-CICA, Rúa As Carballeiras, 15071 A Coruña, Spain.ORCID 0000-0002-4559-8398
Blanca LaffonInstituto de Investigación Biomédica de A Coruña (INIBIC), Oza, 15071 A Coruña, Spain.ORCID 0000-0001-7649-2599
Mónica FolgueiraUniversidade da Coruña, Grupo NEUROVER, Centro Interdisciplinar de Química e Bioloxía-CICA, Rúa As Carballeiras, 15071 A Coruña, Spain.ORCID 0000-0003-2927-7516
Universidade da Coruña · ESUniversidade do Porto · PT

Funding

Centro Interdisciplinar de Química e Bioloxía (CICA) CICA-Disrupting Project 2021SEM-B2Ministerio de Ciencia e Innovación España PID2020-114908GA-I00Ministerio de Educación Cultura y Deporte BEAGAL18/00142Xunta de Galicia ED431B 2022/16Xunta de Galicia ED481A 2019/003
6 · The paper itself

Abstract

Zinc oxide nanoparticles (ZnO NPs) are among the most widely used nanomaterials. They have multiple applications in cosmetics, textiles, paints, electronics and, recently, also in biomedicine. This extensive use of ZnO NPs notably increases the probability that both humans and wildlife are subjected to undesirable effects. Despite being among the most studied NPs from a toxicological point of view, much remains unknown about their ecotoxicological effects or how they may affect specific cell types, such as cells of the central nervous system. The main objective of this work was to investigate the effects of ZnO NPs on human glial cells and zebrafish embryo development and to explore the role of the released Zn

Indexed as

Metal NanoparticlesNanoparticlesZinc OxideAnimalsHumansIonsNeurogliaZebrafishIonsZinc Oxidecytotoxicityhuman A172 glial cellszebrafishzinc oxide nanoparticlesZn2+ ions

Identifiers

PMID37569675
PMCPMC10418813
OpenAlexW4385446556

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.