Evidence map›Paper›PMID 37569647›Full record

ArticleInternational journal of molecular sciences2023

Antiretroviral Treatment-Induced Galectin-9 Might Impact HIV Viremia in Addition to Contributing to Inflammaging.

Ashwini Shete, Vaishnav Wagh, Jyoti Sawant, Pallavi Shidhaye, Suvarna Sane, Amrita Rao, Smita Kulkarni, Manisha Ghate

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ashwini SheteIndian Council of Medical Research, National AIDS Research Institute (ICMR-NARI), Pune 411026, India.ORCID 0000-0003-0791-2128
Vaishnav WaghIndian Council of Medical Research, National AIDS Research Institute (ICMR-NARI), Pune 411026, India.
Jyoti SawantIndian Council of Medical Research, National AIDS Research Institute (ICMR-NARI), Pune 411026, India.ORCID 0000-0003-1702-3631
Pallavi ShidhayeIndian Council of Medical Research, National AIDS Research Institute (ICMR-NARI), Pune 411026, India.ORCID 0000-0002-3903-2830
Suvarna SaneIndian Council of Medical Research, National AIDS Research Institute (ICMR-NARI), Pune 411026, India.
Amrita RaoIndian Council of Medical Research, National AIDS Research Institute (ICMR-NARI), Pune 411026, India.
Smita KulkarniIndian Council of Medical Research, National AIDS Research Institute (ICMR-NARI), Pune 411026, India.
Manisha GhateIndian Council of Medical Research, National AIDS Research Institute (ICMR-NARI), Pune 411026, India.
Indian Council of Medical Research · IN

Funding

Indian Council of Medical Research 70/1/2019-BMS/MIF
6 · The paper itself

Abstract

backgroundGalectin-9 induces HIV reactivation and also contributes to non-AIDS events through inflammaging. Hence, it is important to assess its levels in HIV-infected individuals to determine their association with HIV viremia and other comorbidities.

methodsPlasma galectin-9 levels were estimated in viremic

resultPlasma galectin-9 levels correlated positively with VL (r = 0.507,

conclusionThe galectin-9-to-CD4 count ratio indicated the potential of galectin-9 as a cheaper monitoring tool to detect HIV viremia. Strategies for countering the effects of galectin-9 for controlling HIV viremia and non-AIDS events are urgently warranted.

Indexed as

Anti-HIV AgentsHIV InfectionsAnti-Retroviral AgentsAntiretroviral Therapy, Highly ActiveCD4 Lymphocyte CountHumansViral LoadViremiaAnti-HIV AgentsAnti-Retroviral Agentsantiretroviral therapycystatin CGalectin-9HIV viremiainflammaging

Identifiers

PMID37569647
PMCPMC10418429
OpenAlexW4385455983

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.