Evidence map›Paper›PMID 37569637›Full record

ArticleInternational journal of molecular sciences2023

Reciprocal Regulation of Peroxisome Biogenesis and Myogenic Factors Is Critical for Myogenesis.

Chuan-Che Wu, Wei-Cheng Chen, Wen-Po Hsiao, Kai-Fan Huang, Yi-Shiuan Liao, Huang-Bin Lin, Yi-Ju Wu, Chien-Han Kao, Shen-Liang Chen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. MyoD Over-Expression Rescues GST-bFGF Repressed Myogenesis.International journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Chuan-Che WuDepartment of Life Sciences, College of Health Sciences and Technology, National Central University, Taoyuan 320317, Taiwan.ORCID 0000-0002-6948-247X
Wei-Cheng ChenDepartment of Life Sciences, College of Health Sciences and Technology, National Central University, Taoyuan 320317, Taiwan.ORCID 0000-0002-4043-9179
Wen-Po HsiaoDepartment of Life Sciences, College of Health Sciences and Technology, National Central University, Taoyuan 320317, Taiwan.
Kai-Fan HuangDepartment of Life Sciences, College of Health Sciences and Technology, National Central University, Taoyuan 320317, Taiwan.ORCID 0000-0001-9654-3226
Yi-Shiuan LiaoDepartment of Life Sciences, College of Health Sciences and Technology, National Central University, Taoyuan 320317, Taiwan.
Huang-Bin LinDepartment of Life Sciences, College of Health Sciences and Technology, National Central University, Taoyuan 320317, Taiwan.
Yi-Ju WuDepartment of Life Sciences, College of Health Sciences and Technology, National Central University, Taoyuan 320317, Taiwan.ORCID 0000-0003-2763-855X
Chien-Han KaoDepartment of Life Sciences, College of Health Sciences and Technology, National Central University, Taoyuan 320317, Taiwan.
Shen-Liang ChenDepartment of Life Sciences, College of Health Sciences and Technology, National Central University, Taoyuan 320317, Taiwan.
National Central University · TW

Funding

Ministry of Science and Technology MOST 110-2320-B-008-004-
6 · The paper itself

Abstract

Mitochondria (MITO) and peroxisomes (PEXO) are the major organelles involved in the oxidative metabolism of cells, but detailed examination of their dynamics and functional adaptations during skeletal muscle (SKM) development (myogenesis) is still lacking. In this study, we found that during myogenesis, MITO DNA, ROS level, and redox ratio increased in myotubes, but the membrane potential (Δψm) and ATP content reduced, implying that the MITO efficiency might reduce during myogenesis. The PEXO number and density both increased during myogenesis, which probably resulted from the accumulation and increased biogenesis of PEXO. The expression of PEXO biogenesis factors was induced during myogenesis in vitro and in utero, and their promoters were also activated by MyoD. Knockdown of the biogenesis factors

Indexed as

Muscle Fibers, SkeletalPeroxisomesCell DifferentiationMitochondriaMuscle DevelopmentMuscle, SkeletalcatalasemitochondriamusclemyogenesisperoxisomePex3

Identifiers

PMID37569637
PMCPMC10419124
OpenAlexW4385428951

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.