Evidence map›Paper›PMID 37569572›Full record

ArticleInternational journal of molecular sciences2023

Lipopolysaccharide Tolerance in Human Primary Monocytes and Polarized Macrophages.

Hui Li, Annette Breedijk, Nadine Dietrich, Katja Nitschke, Jonas Jarczyk, Philipp Nuhn, Bernhard K Krämer, Benito A Yard, Jan Leipe, Sibylle Hauske

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Frontiers in immunology · 2025
    Article
  6. Alleviation of LPS-induced Endothelial Injury due to GHRH Antagonist Treatment.International journal of peptide research and therapeutics · 2024
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Hui LiFifth Medical Department, University Hospital Mannheim, Heidelberg University, 68167 Mannheim, Germany.
Annette BreedijkFifth Medical Department, University Hospital Mannheim, Heidelberg University, 68167 Mannheim, Germany.
Nadine DietrichFifth Medical Department, University Hospital Mannheim, Heidelberg University, 68167 Mannheim, Germany.
Katja NitschkeDepartment of Urology, University Hospital Mannheim, Heidelberg University, 68167 Mannheim, Germany.
Jonas JarczykDepartment of Urology, University Hospital Mannheim, Heidelberg University, 68167 Mannheim, Germany.ORCID 0000-0003-4434-7826
Philipp NuhnDepartment of Urology, University Hospital Mannheim, Heidelberg University, 68167 Mannheim, Germany.
Bernhard K KrämerFifth Medical Department, University Hospital Mannheim, Heidelberg University, 68167 Mannheim, Germany.
Benito A YardFifth Medical Department, University Hospital Mannheim, Heidelberg University, 68167 Mannheim, Germany.
Jan LeipeFifth Medical Department, University Hospital Mannheim, Heidelberg University, 68167 Mannheim, Germany.
Sibylle HauskeFifth Medical Department, University Hospital Mannheim, Heidelberg University, 68167 Mannheim, Germany.ORCID 0000-0003-3319-3710
Heidelberg University · DEUniversity of Mannheim · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Innate immune memory allows macrophages to adequately respond to pathogens to which they have been pre-exposed. To what extent different pattern recognition receptors, cytokines and resolution signals influence innate immune memory needs further elucidation. The present study assessed whether lipopolysaccharide (LPS) tolerance in monocytes and macrophages is affected by these factors. Human CD14

Indexed as

LipopolysaccharidesMonocytesCytokinesHumansImmune ToleranceInterleukin-6Lipopolysaccharide ReceptorsMacrophagesTumor Necrosis Factor-alphaCytokinesInterleukin-6Lipopolysaccharide ReceptorsLipopolysaccharidesTumor Necrosis Factor-alphaDHADMIinnate immune memoryLPS tolerancemacrophagesmonocytesTLR agoniststrained immunity

Identifiers

PMID37569572
PMCPMC10419197
OpenAlexW4385422764

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.