Evidence map›Paper›PMID 37569542›Full record

ArticleInternational journal of molecular sciences2023

Detection of Primary DNA Lesions by Transient Changes in Mating Behavior in Yeast

Anna S Zhuk, Anna A Shiriaeva, Yulia V Andreychuk, Olga V Kochenova, Elena R Tarakhovskaya, Vladimir M Bure, Youri I Pavlov, Sergey G Inge-Vechtomov, Elena I Stepchenkova

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. CRISPR/Cas9 as a Mutagenic Factor.International journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Anna S ZhukInstitute of Applied Computer Science, ITMO University, 191002 St. Petersburg, Russia.ORCID 0000-0001-8683-9533
Anna A ShiriaevaDepartment of Genetics and Biotechnology, St. Petersburg State University, 199034 St. Petersburg, Russia.
Yulia V AndreychukLaboratory of Amyloid Biology, St. Petersburg State University, 199034 St. Petersburg, Russia.ORCID 0000-0003-0957-9840
Olga V KochenovaDepartment of Genetics and Biotechnology, St. Petersburg State University, 199034 St. Petersburg, Russia.
Elena R TarakhovskayaVavilov Institute of General Genetics, St. Petersburg Branch, Russian Academy of Sciences, 199034 St. Petersburg, Russia.ORCID 0000-0002-5341-2813
Vladimir M BureFaculty of Applied Mathematics and Control Processes, St. Petersburg State University, 199034 St. Petersburg, Russia.ORCID 0000-0001-7018-4667
Youri I PavlovEppley Institute for Research in Cancer, Fred and Pamela Buffett Cancer Center, the University of Nebraska Medical Center, Omaha, NE 68198, USA.ORCID 0000-0003-1179-5796
Sergey G Inge-VechtomovVavilov Institute of General Genetics, St. Petersburg Branch, Russian Academy of Sciences, 199034 St. Petersburg, Russia.
Elena I StepchenkovaVavilov Institute of General Genetics, St. Petersburg Branch, Russian Academy of Sciences, 199034 St. Petersburg, Russia.ORCID 0000-0002-5854-8701
St Petersburg University · RUHoward Hughes Medical Institute · USUniversity of Nebraska Medical Center · US

Funding

Russian Science Foundation 20-15-00081
6 · The paper itself

Abstract

Spontaneous or induced DNA lesions can result in stable gene mutations and chromosomal aberrations due to their inaccurate repair, ultimately resulting in phenotype changes. Some DNA lesions per se may interfere with transcription, leading to temporary phenocopies of mutations. The direct impact of primary DNA lesions on phenotype before their removal by repair is not well understood. To address this question, we used the alpha-test, which allows for detecting various genetic events leading to temporary or hereditary changes in mating type α→a in heterothallic strains of yeast

Indexed as

Saccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsCell CycleDNADNA RepairDNASaccharomyces cerevisiae Proteinsalpha-testDNA lesionsDNA repairmutationstemporary phenotype modifications

Identifiers

PMID37569542
PMCPMC10418631
OpenAlexW4385399746

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.