Hydrazinolysis Products of Selected Sugar Lactones-Crystal Structure and Microbiological Activity.

Justyna Samaszko-Fiertek, Artur Sikorski, Barbara Dmochowska, Piotr Szweda, Janusz Madaj

Open access · goldAbstract read

In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

–field-weighted citation impact, top 73% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed, 0 citations in OpenAlex.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Justyna Samaszko-FiertekFaculty of Chemistry, University of Gdansk, Wita Stwosza 63, 80-308 Gdansk, Poland.ORCID 0000-0003-0629-9579

Artur SikorskiFaculty of Chemistry, University of Gdansk, Wita Stwosza 63, 80-308 Gdansk, Poland.ORCID 0000-0002-4559-7870

Barbara DmochowskaFaculty of Chemistry, University of Gdansk, Wita Stwosza 63, 80-308 Gdansk, Poland.ORCID 0000-0002-7760-8482

Piotr SzwedaDepartment of Pharmaceutical Technology and Biochemistry, Gdansk University of Technology, Gabriela Narutowicza Street 11/12, 80-233 Gdansk, Poland.ORCID 0000-0001-8291-5148

Janusz MadajFaculty of Chemistry, University of Gdansk, Wita Stwosza 63, 80-308 Gdansk, Poland.ORCID 0000-0002-8775-8951

University of Gdańsk · PLGdańsk University of Technology · PL

Funding

University of Gdansk DS/531-T100-D501-23

6 · The paper itself

Abstract

Commercially available lactones, as well as those synthesized by us, turned out to be good substrates for the synthesis of sugar hydrazides. The exception was L-ascorbic acid, whose hydrazinolysis led to the formation of a hydrazinium salt, not the hydrazide as expected. The structure of all compounds was confirmed by NMR and X-ray analyses. The lower durability of hydrazinium L-ascorbate was additionally confirmed by thermogravimetric tests. All products were tested for biological activity against Gram-negative bacteria strains

Indexed as

Anti-Bacterial AgentsAntifungal AgentsHydrazinesLactonesSugarsCrystallography, X-RayMicrobial Sensitivity TestsStaphylococcus aureusAnti-Bacterial AgentsAntifungal AgentsHydrazinesLactonesSugarsantimicrobial activitycrystallographyhydrazinium ascorbatesugar hydrazidesTG analysis

Identifiers

PMID37569492

DOI10.3390/ijms241512114

PMCPMC10418350

OpenAlexW4385399785

What OpenQuestion holds

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LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.