Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
1 citing paper in PubMed, 5 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
7 authors at 1 institution in 1 country.
Marek MentelDepartment of Biochemistry, Faculty of Natural Sciences, Comenius University in Bratislava, Mlynská Dolina CH1, Ilkovičova 6, 84215 Bratislava, Slovakia.
Miroslava IllováDepartment of Biochemistry, Faculty of Natural Sciences, Comenius University in Bratislava, Mlynská Dolina CH1, Ilkovičova 6, 84215 Bratislava, Slovakia.
Veronika KrajčovičováDepartment of Biochemistry, Faculty of Natural Sciences, Comenius University in Bratislava, Mlynská Dolina CH1, Ilkovičova 6, 84215 Bratislava, Slovakia.ORCID 0000-0002-5019-3635
Gabriela KroupováDepartment of Biochemistry, Faculty of Natural Sciences, Comenius University in Bratislava, Mlynská Dolina CH1, Ilkovičova 6, 84215 Bratislava, Slovakia.
Zuzana MannováDepartment of Biochemistry, Faculty of Natural Sciences, Comenius University in Bratislava, Mlynská Dolina CH1, Ilkovičova 6, 84215 Bratislava, Slovakia.
Petra ChovančíkováDepartment of Biochemistry, Faculty of Natural Sciences, Comenius University in Bratislava, Mlynská Dolina CH1, Ilkovičova 6, 84215 Bratislava, Slovakia.
Peter PolčicDepartment of Biochemistry, Faculty of Natural Sciences, Comenius University in Bratislava, Mlynská Dolina CH1, Ilkovičova 6, 84215 Bratislava, Slovakia.ORCID 0000-0003-0341-7533
Comenius University Bratislava · SK
Funding
European Regional Development Fund ITMS2014+: 313021X329Ministry of Education, Science, Research and Sport of the Slovak Republic VEGA 1/0459/20
6 · The paper itself
Abstract
Permeabilization of mitochondrial membrane by proteins of the BCL-2 family is a key decisive event in the induction of apoptosis in mammalian cells. Although yeast does not have homologs of the BCL-2 family, when these are expressed in yeast, they modulate the survival of cells in a way that corresponds to their activity in mammalian cells. The yeast gene, alternatively referred to as
Indexed as
Hydrogen PeroxideSaccharomyces cerevisiaeAnimalsApoptosisbcl-2-Associated X Proteinbcl-2 Homologous Antagonist-Killer ProteinCell SurvivalMammalsProto-Oncogene Proteins c-bcl-2Saccharomyces cerevisiae Proteinsbcl-2-Associated X Proteinbcl-2 Homologous Antagonist-Killer ProteinBxi1p protein, S cerevisiaeHydrogen PeroxideProto-Oncogene Proteins c-bcl-2Saccharomyces cerevisiae ProteinsapoptosisBcl-2 familyendoplasmic reticulumregulated cell deathSaccharomyces cerevisiaeunfolded protein responseyeast
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Yeast Bax Inhibitor (Bxi1p/Ybh3p) Is Not Required for the Action of Bcl-2 Family Proteins on Cell Viability. · full record | OpenQuestion