Evidence map›Paper›PMID 37569377›Full record

ReviewInternational journal of molecular sciences2023

A Comprehensive Review of Inorganic Sonosensitizers for Sonodynamic Therapy.

Peng Chen, Ping Zhang, Navid Hussain Shah, Yanyan Cui, Yaling Wang

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Method for Isolating Hypericin fromMolecules (Basel, Switzerland) · 2026
    Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Sonodynamic biomimetic-nanomedicine fight cancers.Journal of nanobiotechnology · 2025
    Review
  16. Ultrasound-Activated BiOI/TiMaterials (Basel, Switzerland) · 2025
    Article
  17. Current Research in Drug-Free Cancer Therapies.Bioengineering (Basel, Switzerland) · 2025
    Review
  18. Review
  19. Article
  20. Enhanced Sonodynamic Therapy via Au Nanoclusters Deposited on TiOInternational journal of nanomedicine · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Peng ChenBeijing Engineering Research Center of Mixed Reality and Advanced Display, School of Optics and Photonics, Beijing Institute of Technology, Beijing 100081, China.
Ping ZhangBeijing Engineering Research Center of Mixed Reality and Advanced Display, School of Optics and Photonics, Beijing Institute of Technology, Beijing 100081, China.
Navid Hussain ShahBeijing Engineering Research Center of Mixed Reality and Advanced Display, School of Optics and Photonics, Beijing Institute of Technology, Beijing 100081, China.
Yanyan CuiBeijing Engineering Research Center of Mixed Reality and Advanced Display, School of Optics and Photonics, Beijing Institute of Technology, Beijing 100081, China.ORCID 0000-0001-6634-9131
Yaling WangCAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology of China, Beijing 100190, China.

Funding

Beijing Natural Science Foundation L212015CAMS Innovation Fund for Medical Sciences CIFMS 2019-I2M-5-018Key-Area Research and Development Program of Guangdong Province for Guangdong high level Innovation Research Institute 2020B0909010001National Basic Research Program of China 2021YFA1200900National Natural Science Foundation of China 22027810, 11621505Program for International S&T Cooperation Projects of the Ministry of Science and Technology of China 2018YFE0117200Research and Development Project in Key Areas of Guangdong Province 2019B090917011Strategic Priority Research Program of Chinese Academy of Sciences XDB36000000
6 · The paper itself

Abstract

Sonodynamic therapy (SDT) is an emerging non-invasive cancer treatment method in the field of nanomedicine, which has the advantages of deep penetration, good therapeutic efficacy, and minimal damage to normal tissues. Sonosensitizers play a crucial role in the process of SDT, as their structure and properties directly determine the treatment outcome. Inorganic sonosensitizers, with their high stability and longer circulation time in the human body, have great potential in SDT. In this review, the possible mechanisms of SDT including the ultrasonic cavitation, reactive oxygen species generation, and activation of immunity are briefly discussed. Then, the latest research progress on inorganic sonosensitizers is systematically summarized. Subsequently, strategies for optimizing treatment efficacy are introduced, including combination therapy and image-guided therapy. The challenges and future prospects of sonodynamic therapy are discussed. It is hoped that this review will provide some guidance for the screening of inorganic sonosensitizers.

Indexed as

NeoplasmsUltrasonic TherapyCombined Modality TherapyHumansNanomedicineReactive Oxygen SpeciesTheranostic NanomedicineReactive Oxygen Speciescombination therapyinorganic sonosensitizersSDT mechanismssonodynamic therapy

Identifiers

PMID37569377
PMCPMC10418994

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.