Evidence map›Paper›PMID 37569316›Full record

ArticleInternational journal of molecular sciences2023

Dysregulated miRNA and mRNA Expression Affect Overlapping Pathways in a Huntington's Disease Model.

Nóra Zsindely, Gábor Nagy, Fruzsina Siági, Anita Farkas, László Bodai

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Decoding Nucleotide Repeat Expansion Diseases: Novel Insights fromInternational journal of molecular sciences · 2024
    Review
  6. The Role of miR-137 in Neurodegenerative Disorders.International journal of molecular sciences · 2024
    Review
  7. Non-coding RNAs and neuroinflammation: implications for neurological disorders.Experimental biology and medicine (Maywood, N.J.) · 2024
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Nóra ZsindelyDepartment of Genetics, Faculty of Science and Informatics, University of Szeged, H-6726 Szeged, Hungary.ORCID 0000-0002-6189-3100
Gábor NagyDepartment of Biochemistry and Molecular Biology, Faculty of Science and Informatics, University of Szeged, H-6726 Szeged, Hungary.ORCID 0000-0001-5464-1135
Fruzsina SiágiDepartment of Biochemistry and Molecular Biology, Faculty of Science and Informatics, University of Szeged, H-6726 Szeged, Hungary.
Anita FarkasDepartment of Biochemistry and Molecular Biology, Faculty of Science and Informatics, University of Szeged, H-6726 Szeged, Hungary.
László BodaiDepartment of Biochemistry and Molecular Biology, Faculty of Science and Informatics, University of Szeged, H-6726 Szeged, Hungary.ORCID 0000-0001-8411-626X
University of Szeged · HU

Funding

Hungarian Academy of Sciences BO/00522/19/8Ministry for Innovation and Technology [Hungary] UNKP-21-5-SZTE-574National Research, Development and Innovation Office GINOP-2.3.2-15-2016-00032National Research, Development and Innovation Office GINOP-2.3.2-15-2016-00034
6 · The paper itself

Abstract

Huntington's disease (HD) is a fatal neurodegenerative disorder caused by the expansion of a CAG trinucleotide repeat in the Huntingtin gene. Transcriptional dysregulation is one of the main cellular processes affected by mutant Huntingtin (mHtt). In this study, we investigate the alterations in miRNA and mRNA expression levels in a

Indexed as

Huntington DiseaseMicroRNAsAnimalsDisease Models, AnimalHuntingtin ProteinRNA, MessengerTrinucleotide RepeatsHuntingtin ProteinMicroRNAsRNA, Messengeranimal modelDrosophilaHuntington’s diseasemiRNAneurodegenerationtranscriptiontranscriptomics

Identifiers

PMID37569316
PMCPMC10419151
OpenAlexW4385366180

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.